Global Patent Index - EP 0914041 A4

EP 0914041 A4 20000628 - METHODS AND COMPOSITIONS FOR SUPPRESSING AN IMMUNE RESPONSE USING MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) CLASS II PEPTIDES

Title (en)

METHODS AND COMPOSITIONS FOR SUPPRESSING AN IMMUNE RESPONSE USING MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) CLASS II PEPTIDES

Title (de)

VERFAHREN UND ZUSAMMENSETZUNG ZUR UNTERDRUCKUNG DER IMMUNANTWORT UNTER VERWENDUNG VON PEPTIDEN DER KLASSE II DES HAUPTHISTOKOMPATABILITATSKOMPLEXES (MHC)

Title (fr)

PROCEDES ET COMPOSITIONS DE SUPPRESSION D'UNE REPONSE IMMUNE A L'AIDE DE PEPTIDES DE LA CLASSE II DU COMPLEXE MAJEUR D'HISTOCOMPATIBILITE

Publication

EP 0914041 A4 20000628 (EN)

Application

EP 96933201 A 19960923

Priority

  • US 9615662 W 19960923
  • US 411795 P 19950921

Abstract (en)

[origin: WO9710711A1] Methods and compositions for suppressing an immune response using or comprising peptide fragments of the alpha chain of class II major histocompatibility complex containing a highly conserved motif and effective to suppress at least one and preferably all of the following: a mixed lymphocyte reaction or other T-cell allorecognition reaction; generation of cytotoxic T-cells recognizing an alloantigen; lymphocyte proliferation against tissue antigen; and stimulatory cytokine production by lymphocytes. Immune responses that can be abated or suppressed include alloimmunity and autoimmunity.

IPC 1-7

A01N 37/18; A61K 38/00; A61K 38/04; A61K 39/00; C07K 2/00; C07K 4/00; C07K 5/00; C07K 7/00; C07K 14/00; C07K 16/00; C07K 17/00

IPC 8 full level

A61K 38/00 (2006.01); A61K 31/00 (2006.01); A61K 39/00 (2006.01); A61P 37/00 (2006.01); A61P 37/06 (2006.01); C07K 7/08 (2006.01); C07K 14/74 (2006.01)

CPC (source: EP KR)

A61K 38/00 (2013.01 - KR); A61P 37/00 (2017.12 - EP); A61P 37/06 (2017.12 - EP); C07K 14/70539 (2013.01 - EP KR); A61K 38/00 (2013.01 - EP)

Citation (search report)

  • [X] WO 9404557 A1 19940303 - HARVARD COLLEGE [US]
  • [X] ROSLONIEC, EDWARD F. ET AL.: "MHC CLASS II-DERIVED PEPTIDES CAN BIND TO CLASS II MOLECULES INCLUDING SELF MOLECULES AND PREVENT ANTIGEN PRESENTATION", J EXP MED (1990) 171(5) 1419-30, XP000892195
  • [X] LI, WAN FEN ET AL.: "MODULATION OF CLASS II RESTRICTED T CELL RESPONSES BY PEPTIDES DERIVED FROM SELF CLASS II MOLECULE", EUR J IMMUNOL (1992) 22(10) 2527-31, XP000892199
  • [X] BENICHOU, GILLES ET AL.: "IMMUNOGENICITY AND TOLEROGENICITY OF SELF-MAJOR HISTOCOMPATIBILITY COMPLEX PEPTIDES", J EXP MED (1990) 172(5) 1341-6, XP000906710
  • See references of WO 9710711A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9710711 A1 19970327; AU 7202596 A 19970409; BR 9610625 A 19990316; CA 2230119 A1 19970327; EP 0914041 A1 19990512; EP 0914041 A4 20000628; HU P9901795 A2 19990928; IL 123759 A0 19981030; JP H11513377 A 19991116; KR 19990063637 A 19990726; NO 981201 D0 19980317; NO 981201 L 19980317

DOCDB simple family (application)

US 9615662 W 19960923; AU 7202596 A 19960923; BR 9610625 A 19960923; CA 2230119 A 19960923; EP 96933201 A 19960923; HU P9901795 A 19960923; IL 12375996 A 19960923; JP 51297697 A 19960923; KR 19980702086 A 19980320; NO 981201 A 19980317