Global Patent Index - EP 0914041 A4

EP 0914041 A4 2000-06-28 - METHODS AND COMPOSITIONS FOR SUPPRESSING AN IMMUNE RESPONSE USING MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) CLASS II PEPTIDES

Title (en)

METHODS AND COMPOSITIONS FOR SUPPRESSING AN IMMUNE RESPONSE USING MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) CLASS II PEPTIDES

Title (de)

VERFAHREN UND ZUSAMMENSETZUNG ZUR UNTERDRUCKUNG DER IMMUNANTWORT UNTER VERWENDUNG VON PEPTIDEN DER KLASSE II DES HAUPTHISTOKOMPATABILITATSKOMPLEXES (MHC)

Title (fr)

PROCEDES ET COMPOSITIONS DE SUPPRESSION D'UNE REPONSE IMMUNE A L'AIDE DE PEPTIDES DE LA CLASSE II DU COMPLEXE MAJEUR D'HISTOCOMPATIBILITE

Publication

EP 0914041 A4 (EN)

Application

EP 96933201 A

Priority

  • US 9615662 W
  • US 411795 P

Abstract (en)

[origin: WO9710711A1] Methods and compositions for suppressing an immune response using or comprising peptide fragments of the alpha chain of class II major histocompatibility complex containing a highly conserved motif and effective to suppress at least one and preferably all of the following: a mixed lymphocyte reaction or other T-cell allorecognition reaction; generation of cytotoxic T-cells recognizing an alloantigen; lymphocyte proliferation against tissue antigen; and stimulatory cytokine production by lymphocytes. Immune responses that can be abated or suppressed include alloimmunity and autoimmunity.

IPC 1-7 (main, further and additional classification)

A01N 37/18; A61K 38/00; A61K 38/04; A61K 39/00; C07K 2/00; C07K 4/00; C07K 5/00; C07K 7/00; C07K 14/00; C07K 16/00; C07K 17/00

IPC 8 full level (invention and additional information)

A61K 38/00 (2006.01); A61K 31/00 (2006.01); A61K 39/00 (2006.01); A61P 37/00 (2006.01); A61P 37/06 (2006.01); C07K 7/08 (2006.01); C07K 14/74 (2006.01)

CPC (invention and additional information)

C07K 14/70539 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

  • [X] WO 9404557 A1 19940303 - HARVARD COLLEGE [US]
  • [X] ROSLONIEC, EDWARD F. ET AL.: "MHC CLASS II-DERIVED PEPTIDES CAN BIND TO CLASS II MOLECULES INCLUDING SELF MOLECULES AND PREVENT ANTIGEN PRESENTATION", J EXP MED (1990) 171(5) 1419-30, XP000892195
  • [X] LI, WAN FEN ET AL.: "MODULATION OF CLASS II RESTRICTED T CELL RESPONSES BY PEPTIDES DERIVED FROM SELF CLASS II MOLECULE", EUR J IMMUNOL (1992) 22(10) 2527-31, XP000892199
  • [X] BENICHOU, GILLES ET AL.: "IMMUNOGENICITY AND TOLEROGENICITY OF SELF-MAJOR HISTOCOMPATIBILITY COMPLEX PEPTIDES", J EXP MED (1990) 172(5) 1341-6, XP000906710
  • See also references of WO 9710711A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9710711 A1 19970327; AU 7202596 A 19970409; BR 9610625 A 19990316; CA 2230119 A1 19970327; EP 0914041 A1 19990512; EP 0914041 A4 20000628; HU 9901795 A2 19990928; IL 123759 D0 19981030; JP H11513377 A 19991116; NO 981201 A 19980317; NO 981201 D0 19980317

INPADOC legal status


2002-10-09 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20020403

2002-01-02 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: AUTOIMMUNE, INC.

2000-06-28 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20000511

2000-06-28 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

1999-05-12 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19980319

1999-05-12 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE