Global Patent Index - EP 0914611 A4

EP 0914611 A4 20021016 - LEPTIN ASSAY

Title (en)

LEPTIN ASSAY

Title (de)

TRANSAKTIVIERUNG VON LEPTIN

Title (fr)

DOSAGE DE LA LEPTINE

Publication

EP 0914611 A4 20021016 (EN)

Application

EP 97924507 A 19970418

Priority

  • GB 9611785 A 19960606
  • US 9706505 W 19970418
  • US 1605196 P 19960422
  • US 3100296 P 19961115

Abstract (en)

[origin: WO9740380A1] A trans-activation assay for leptin is described. Leptin response elements are located proximal to a promoter, and the promoter region is operatively linked to a reporter gene. When leptin binds with the receptor, the reporter gene is transcribed.

IPC 1-7

G01N 33/53; C12N 1/20; C12N 15/00; C12N 15/12; C12N 15/19; C07K 14/575; G01N 33/74

IPC 8 full level

C12N 15/09 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/566 (2006.01)

CPC (source: EP)

C07K 14/4705 (2013.01); C07K 14/715 (2013.01); C12Q 1/6897 (2013.01)

Citation (search report)

  • [A] JAMES N. IHLE: "Cytokine receptor signalling", NATURE, vol. 377, 1995, pages 591 - 594, XP001093912
  • [A] MIYAMOTO ET AL: "REGULATED EXPRESSION OF A GENE ENCODING A NUCLEAR FACTOR, IRF-1, THAT SPECIFICALLY BINDS TO IFN-BETA GENE REGULATORY ELEMENTS", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 54, 1988, pages 903 - 913, XP002101356, ISSN: 0092-8674
  • [A] DARNELL J E ET AL: "JAK-STAT PATHWAYS AND TRANSCRIPTIONAL ACTIVATION IN RESPONSE TO IFNS AND OTHER EXTRACELLULAR SIGNALING PROTEINS", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 264, 3 June 1994 (1994-06-03), pages 1415 - 1421, XP000602106, ISSN: 0036-8075
  • [A] LA BROUSSE ET AL: "Identification of the promoter of the mouse obese gene", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, 30 April 1996 (1996-04-30), pages 4096 - 4101, XP002110083, ISSN: 0027-8424
  • [A] DW GONG, S BI, RE PRATLEY, BD WEINTRAUB: "genomic structure and promoter analysis of the human obese gene", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 8, 1996, pages 3971 - 3974, XP002208626
  • [A] Y. HE, H. CHEN, M.J. QUON, M. REITMAN: "the mouse obese gene", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 270, no. 48, 1995, pages 28887 - 28891, XP002208627
  • See references of WO 9740380A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9740380 A1 19971030; CA 2252443 A1 19971030; EP 0914611 A1 19990512; EP 0914611 A4 20021016; JP 2000511406 A 20000905

DOCDB simple family (application)

US 9706505 W 19970418; CA 2252443 A 19970418; EP 97924507 A 19970418; JP 53820397 A 19970418