EP 0918770 A1 19990602 - PYRIDYL-PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIALS
Title (en)
PYRIDYL-PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIALS
Title (de)
PYRIDYL-PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATE UND IHRE VERWENDUNG ALS ANTIBAKTERIELLE MITTEL
Title (fr)
DERIVES DE PYRIDYLE-PIPERAZINYLE-PHENYLE-OXAZOLIDINONE ET LEUR UTILISATION EN TANT QU'ANTIBACTERIENS
Publication
Application
Priority
- GB 9701769 W 19970701
- GB 9614236 A 19960706
Abstract (en)
[origin: WO9801447A1] The invention concerns a compound of formula (I) wherein, for example: R<1> is of the formula -NHC(=O)R<a> wherein R<a> is for example (1-4C)alkyl; R<2> and R<3> hydrogen or fluoro; R<4> and R<5> are independently are independently hydrogen or methyl; R<6> is pyridyl, optionally substituted by substituents selected from (1-4C)alkyl (optionally substituted), halo, trifluoromethyl, (1-4C)alkylS(O)n- (wherein n is 0, 1 or 2), (1-4C)alkylS(O)2amino, (1-4C)alkanoylamino, carboxy, hydroxy, amino, (1-4C)alkylamino, di-(1-4C)alkylamino, (1-4C)alkoxycarbonyl, carbamoyl, <u>N</u>-(1-4C)alkylcarbamoyl, di-(<u>N</u>-(1-4C)alkyl)carbamoyl [wherein the (1-4C)alkyl group or groups in the last two-mentioned carbamoyl substituents is optionally substituted by hydroxy, (1-4C)alkoxy or (1-4C)alkoxycarbonyl], (2-4C)alkenyl (optionally substituted by carboxy or (1-4C)alkoxycarbonyl), (1-4C)alkoxy, cyano or nitro; pharmaceutically-acceptable salts, suitable N-oxides and in vivo hydrolysable esters thereof; processes for their preparation; pharmaceutical compositions containing them and their use as antibacterial agents.
IPC 1-7
IPC 8 full level
A61K 31/496 (2006.01); A61P 31/04 (2006.01); C07D 413/12 (2006.01)
CPC (source: EP)
A61P 31/04 (2017.12); C07D 413/12 (2013.01)
Citation (search report)
See references of WO 9801447A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB IT LI NL PT SE
DOCDB simple family (publication)
WO 9801447 A1 19980115; AU 3352197 A 19980202; EP 0918770 A1 19990602; GB 9614236 D0 19960904; JP 2000514084 A 20001024; ZA 975951 B 19980106
DOCDB simple family (application)
GB 9701769 W 19970701; AU 3352197 A 19970701; EP 97929405 A 19970701; GB 9614236 A 19960706; JP 50490198 A 19970701; ZA 975951 A 19970703