Title (en)

STEREOSELECTIVE DEOXYGENATION REACTION

Title (de)

STEREOSELEKTIVE DEOXYGENIERUNGSREAKTION

Title (fr)

REACTION DE DESOXYGENATION STEREOSELECTIVE

Publication

EP 0923557 A1 19990623 (EN)

Application

EP 97937187 A 19970808

Priority

• GB 9617900 A 19960828
• GB 9625806 A 19961212
• US 9714045 W 19970808
• US 2361496 P 19960809
• US 2843896 P 19961010

Abstract (en)

[origin: WO9806700A1] This invention relates to a key intermediate in the synthesis of an endothelin antagonist, the synthesis of this key intermediate and the synthesis of an endothelin antagonist using this intermediate in a stereoselective deoxygenation reaction.

IPC 1-7

C07D 221/02; C07D 471/00; A61K 31/335; A61K 31/435

IPC 8 full level

C07D 221/04 (2006.01); A61K 31/00 (2006.01); A61K 31/42 (2006.01); A61K 31/421 (2006.01); A61K 31/423 (2006.01); A61K 31/435 (2006.01); A61P 43/00 (2006.01); C07D 263/52 (2006.01); C07D 405/04 (2006.01); C07D 405/06 (2006.01); C07D 405/12 (2006.01); C07D 413/06 (2006.01); C07D 413/14 (2006.01)

CPC (source: EP)

A61P 43/00 (2017.12); C07D 405/04 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9806700 A1 19980219; AU 3975797 A 19980306; AU 711936 B2 19991028; CA 2262676 A1 19980219; EP 0923557 A1 19990623; EP 0923557 A4 19991208; JP H11514676 A 19991214

DOCDB simple family (application)

US 9714045 W 19970808; AU 3975797 A 19970808; CA 2262676 A 19970808; EP 97937187 A 19970808; JP 50991598 A 19970808