Title (en)

STEREOSELECTIVE DEOXYGENATION REACTION

Title (de)

STEREOSELEKTIVE DEOXYGENIERUNGSREAKTION

Title (fr)

REACTION DE DESOXYGENATION STEREOSELECTIVE

Publication

EP 0923557 A4 19991208 (EN)

Application

EP 97937187 A 19970808

Priority

• GB 9617900 A 19960828
• GB 9625806 A 19961212
• US 9714045 W 19970808
• US 2361496 P 19960809
• US 2843896 P 19961010

Abstract (en)

[origin: WO9806700A1] This invention relates to a key intermediate in the synthesis of an endothelin antagonist, the synthesis of this key intermediate and the synthesis of an endothelin antagonist using this intermediate in a stereoselective deoxygenation reaction.

IPC 1-7

C07D 221/02; C07D 471/00; A61K 31/335; A61K 31/435

IPC 8 full level

C07D 221/04 (2006.01); A61K 31/00 (2006.01); A61K 31/42 (2006.01); A61K 31/421 (2006.01); A61K 31/423 (2006.01); A61K 31/435 (2006.01); A61P 43/00 (2006.01); C07D 263/52 (2006.01); C07D 405/04 (2006.01); C07D 405/06 (2006.01); C07D 405/12 (2006.01); C07D 413/06 (2006.01); C07D 413/14 (2006.01)

CPC (source: EP)

A61P 43/00 (2017.12); C07D 405/04 (2013.01)

Citation (search report)

• [PX] WO 9717342 A1 19970515 - SMITHKLINE BEECHAM CORP [US], et al
• [E] WO 9737665 A1 19971016 - BANYU PHARMA CO LTD [JP], et al
• [A] WO 9308799 A1 19930513 - SMITHKLINE BEECHAM CORP [US]
• See references of WO 9806700A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9806700 A1 19980219; AU 3975797 A 19980306; AU 711936 B2 19991028; CA 2262676 A1 19980219; EP 0923557 A1 19990623; EP 0923557 A4 19991208; JP H11514676 A 19991214

DOCDB simple family (application)

US 9714045 W 19970808; AU 3975797 A 19970808; CA 2262676 A 19970808; EP 97937187 A 19970808; JP 50991598 A 19970808