EP 0923591 A4 20010131 - NOVEL BORONIC ACID-CONTAINING NUCLEIC ACIDS AND THEIR USE AS DIAGNOSTIC AGENTS
Title (en)
NOVEL BORONIC ACID-CONTAINING NUCLEIC ACIDS AND THEIR USE AS DIAGNOSTIC AGENTS
Title (de)
NEUE BORSAEURE-HALTIGE NUKLEINSAEUREN UND IHRE ANWENDUNG ALS DIAGNOSTISCHE MITTEL
Title (fr)
NOUVEAUX ACIDES NUCLEIQUES CONTENANT DE L'ACIDE BORIQUE ET LEUR UTILISATION COMME AGENTS DIAGNOSTIQUES
Publication
Application
Priority
- US 9712834 W 19970731
- US 69242996 A 19960805
Abstract (en)
[origin: US5876938A] Modified nucleotides and polynucleotides which are useful in hybridization assays for the detection of target genes are provided. The modified polynucleotides contain at least one boronic acid moiety which is attached to a nucleotide base in a position which does not interfere with the hydrogen bonding capabilities of that base during duplex formation. The modified polynucleotides are typically formed from naturally occurring nucleotides and one or more modified nucleotides.
IPC 1-7
C07H 1/00; C07G 3/00; C07H 15/00; C07H 19/00; C07H 21/02; C07H 23/00; C12Q 1/68
IPC 8 full level
C07H 19/06 (2006.01); C07H 19/10 (2006.01); C07H 19/14 (2006.01); C07H 19/16 (2006.01); C07H 19/20 (2006.01); C07H 21/00 (2006.01); C07H 23/00 (2006.01); C12N 15/09 (2006.01); C12P 19/34 (2006.01); C12Q 1/68 (2006.01)
CPC (source: EP US)
C07H 21/00 (2013.01 - EP US); C07H 23/00 (2013.01 - EP US); C12P 19/34 (2013.01 - EP US)
Citation (search report)
- [A] WO 9515333 A1 19950608 - UNIV EMORY [US]
- [A] WO 9401413 A1 19940120 - BORON BIOLOG INC [US], et al
- [A] US 5466679 A 19951114 - SOLOWAY ALBERT H [US], et al
- See references of WO 9805672A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
US 5876938 A 19990302; AU 3809097 A 19980225; AU 729907 B2 20010215; CA 2262618 A1 19980212; CA 2262618 C 20071002; EP 0923591 A1 19990623; EP 0923591 A4 20010131; JP 2000515546 A 20001121; US 5831045 A 19981103; US 5831046 A 19981103; WO 9805672 A1 19980212
DOCDB simple family (application)
US 83734097 A 19970411; AU 3809097 A 19970731; CA 2262618 A 19970731; EP 97935061 A 19970731; JP 50794598 A 19970731; US 69242996 A 19960805; US 83400197 A 19970411; US 9712834 W 19970731