EP 0925300 A4 19990630 -
Publication
Application
Priority
- US 9702678 W 19970214
- US 60199296 A 19960215
Abstract (en)
[origin: WO9730054A1] The present invention relates to pharmaceutically acceptable compounds, including certain substituted indolinyl and derivatives thereof, 1,2,3,4-tetrahydroquinolinyl and derivatives thereof, 1,2,3,4-tetrahydroisoquinolinyl, benz[cd]indolinyl and 5,6-dihydrophenanthridinyl compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are particularly useful for the treatment or prophylaxis of neurological injury and neurodegenerative disorders.
IPC 1-7
IPC 8 full level
C07D 209/08 (2006.01); C07D 209/90 (2006.01); C07D 209/92 (2006.01); C07D 215/08 (2006.01); C07D 215/12 (2006.01); C07D 221/12 (2006.01); C07D 223/22 (2006.01); C07D 225/08 (2006.01); C07D 265/36 (2006.01); C07D 277/62 (2006.01); C07D 279/16 (2006.01); C07D 281/10 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 521/00 (2006.01)
CPC (source: EP KR)
A61P 9/00 (2017.12 - EP); A61P 25/04 (2017.12 - EP); C07D 209/08 (2013.01 - EP KR); C07D 209/90 (2013.01 - EP KR); C07D 209/92 (2013.01 - EP); C07D 215/06 (2013.01 - KR); C07D 215/08 (2013.01 - EP); C07D 215/12 (2013.01 - EP); C07D 221/12 (2013.01 - EP KR); C07D 223/22 (2013.01 - EP); C07D 225/08 (2013.01 - EP); C07D 231/12 (2013.01 - EP); C07D 231/56 (2013.01 - KR); C07D 233/56 (2013.01 - EP KR); C07D 249/08 (2013.01 - EP); C07D 265/36 (2013.01 - EP KR); C07D 277/62 (2013.01 - EP KR); C07D 279/16 (2013.01 - EP KR); C07D 281/10 (2013.01 - EP); C07D 401/12 (2013.01 - EP KR); C07D 403/12 (2013.01 - EP KR); C07D 405/12 (2013.01 - EP)
Citation (search report)
- [DX] WO 9520950 A1 19950810 - CAMBRIDGE NEUROSCIENCE INC [US], et al
- [X] US 3679692 A 19720725 - WU YAO HUA, et al
- [X] US 3291799 A 19661213 - WILHELM WENNER
- [X] US 3314963 A 19670418 - KOCH RICHARD C
- [X] FR 1473839 A 19670324 - ALPHACHIMIE
- [X] N. LAXMA REDDY ET AL.: "Synthesis and structure-activity studies of N,N'-diarylguanidine derivatives. N-(1-Naphthyl)-N'-(3-ethylphenyl)-N'-methylguanidine: a new, selective noncompetitive NMDA receptor antagonist", J. MED. CHEM., vol. 37, no. 2, 1994, pages 260 - 267, XP002098955
- [X] CHEMICAL ABSTRACTS, vol. 89, no. 25, 18 December 1978, Columbus, Ohio, US; abstract no. 215197t, page 575; XP002098957 & VASIL'EVA, V. F. ET AL.: "Substituted 1,2,3,4-tetrahydroquinolines. V. N-Carboxamidines and guanidines. Synthesis and pharmacological properties", KHIM.-FARM. ZH., vol. 12, no. 8, 18 December 1978 (1978-12-18), pages 40 - 45
- [X] R. D. GANO ET AL.: "Guanidines derived from N-cyanotetrahydroquinolines", J. AMER. CHEM. SOC., vol. 74, 1952, pages 3176 - 3177, XP002098956
- See references of WO 9730054A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9730054 A1 19970821; AU 2278097 A 19970902; AU 733475 B2 20010517; EP 0925300 A1 19990630; EP 0925300 A4 19990630; JP 2000504730 A 20000418; KR 19990082494 A 19991125
DOCDB simple family (application)
US 9702678 W 19970214; AU 2278097 A 19970214; EP 97906923 A 19970214; JP 52960297 A 19970214; KR 19980706227 A 19980812