EP 0930892 A1 19990728 - CYTOKINE ENHANCED IMMUNOTHERAPY FOR BRAIN TUMORS
Title (en)
CYTOKINE ENHANCED IMMUNOTHERAPY FOR BRAIN TUMORS
Title (de)
ZYTOKIN-ERHOEHTE IMMUNTHERAPIE GEGEN GEHIRNTUMORE
Title (fr)
IMMUNOTHERAPIE AMELIOREE PAR CYTOKINE POUR TUMEURS CEREBRALES
Publication
Application
Priority
- US 9718455 W 19971015
- US 73159796 A 19961016
Abstract (en)
[origin: WO9816246A1] A therapy for treatment of patients with cancer utilizing the combination of a cytokine in a pharmaceutically acceptable carrier for systemic administration and a cytokine in a pharmaceutically acceptable carrier for local administration is described. In the most preferred embodiment, brain tumors are treated with a cytokine such as GM-CSF administered systemically, most preferably in combination with tumor antigen such as replication incompetent tumor cells, and a cytokine such as IL-2 or IL-4 administered locally, most preferably in a vehicle providing release over a period of time, such as transduced cells, again most preferably replication incompetent tumor cells, or incorporated into microparticulate vehicles such as polymeric microspheres.
IPC 1-7
IPC 8 full level
A61K 9/50 (2006.01); A61K 9/00 (2006.01); A61K 35/12 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 47/30 (2006.01); A61P 35/00 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP US)
A61K 9/0085 (2013.01 - EP); A61K 39/0011 (2013.01 - EP US); A61P 35/00 (2018.01 - EP); A61K 48/00 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9816246 A1 19980423; AU 4818297 A 19980511; CA 2267977 A1 19980423; EP 0930892 A1 19990728; JP 2001502331 A 20010220
DOCDB simple family (application)
US 9718455 W 19971015; AU 4818297 A 19971015; CA 2267977 A 19971015; EP 97910921 A 19971015; JP 51850498 A 19971015