EP 0931263 A1 19990728 - METHOD OF SCREENING FOR SIDE EFFECTS OF ANTICONCEPTIVES OR ESTROGEN AND/OR PROGESTERONE REPLACEMENTS OR SUPPLEMENTS
Title (en)
METHOD OF SCREENING FOR SIDE EFFECTS OF ANTICONCEPTIVES OR ESTROGEN AND/OR PROGESTERONE REPLACEMENTS OR SUPPLEMENTS
Title (de)
SCREENINGSFERFAHREN FÜR NEBENWIRKUNGEN VON ANTIKONZEPTIONSMITTELN ODER ÖSTROGEN UND/ODER PROGESTERON ERSATZ- ODER ZUSATZMITTELN
Title (fr)
METHODE POUR DETECTER LES EFFETS SECONDAIRES DES CONTRACEPTIFS ET DES SUBSTITUTS OU SUPPLEMENTATIONS D'OESTROGENES ET/OU DE PROGESTERONE
Publication
Application
Priority
NL 9600350 W 19960906
Abstract (en)
[origin: WO9810293A1] A method for screening for negative side effects of a sex steroid compound or composition in a subject, by carrying out an assay on the subject or on a sample derived from the subject determining whether an increase of the compound or composition on the level of an acute phase reactant or a metabolic derivative thereof has occurred since applying the compound or composition to the subject, said acute phase reactant being selected from the group consisting of positive Acute Phase Reactants (APRs) with the exclusion of ceruloplasmin and coagulation/thrombosis associated factors, whereby an increase in the level of the acute phase reactant is indicative of negative side effects. A sex steroid compound or composition characterised by a lower increase in APR level as determined in a manner according to the invention than a third generation oral contraceptive, said compound or composition not being a second generation oral contraceptive.
IPC 1-7
IPC 8 full level
G01N 33/50 (2006.01); G01N 33/15 (2006.01); G01N 33/74 (2006.01)
CPC (source: EP)
G01N 33/743 (2013.01)
Citation (search report)
See references of WO 9810293A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9810293 A1 19980312; AU 6947596 A 19980326; AU 733553 B2 20010517; CA 2265516 A1 19980312; CA 2265516 C 20040203; EP 0931263 A1 19990728; JP 2002505736 A 20020219
DOCDB simple family (application)
NL 9600350 W 19960906; AU 6947596 A 19960906; CA 2265516 A 19960906; EP 96930447 A 19960906; JP 51250898 A 19960906