EP 0932670 A4 19990804 -
Publication
Application
Priority
- US 62143096 A 19960325
- US 79240997 A 19970203
- US 9704494 W 19970320
Abstract (en)
[origin: WO9735957A1] The invention provides a number of strategies for transferring and/or evolving gene(s) associated with cellular DNA uptake so that they confer or enhance DNA-uptake capacity of a recipient cell. Evolution is achieved by recursive cycles of recombination and screening/selection. One such strategy entails evolving genes that confer competence in one species to confer either greater competence in that species, or comparable or greater competence in a second species. Another strategy entails evolving genes for use as components of a cloning vector to confer enhanced uptake of the vector. Other strategies entail evolving viral receptors, viruses, and genes that mediate conjugal transfer.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/10 (2006.01); C12N 15/52 (2006.01); C12N 15/64 (2006.01); C12Q 1/68 (2006.01)
CPC (source: EP US)
C12N 15/1027 (2013.01 - EP US); C12N 15/1034 (2013.01 - EP US); C12N 15/1058 (2013.01 - EP US); C12N 15/52 (2013.01 - EP US); C12N 15/64 (2013.01 - EP US)
Citation (search report)
- [XY] WO 9325682 A2 19931223 - UNIV NEW YORK [US], et al
- [X] WO 9534648 A1 19951221 - DADE INT INC [US]
- [Y] WO 9522625 A1 19950824 - AFFYMAX TECH NV [NL], et al
- [A] WO 9600294 A1 19960104 - MEDICAL RES COUNCIL [GB], et al
- [PX] WO 9710330 A1 19970320 - BIOINVENT INT AB [SE], et al
- [E] WO 9720078 A1 19970605 - AFFYMAX TECH NV [NL], et al
- [LE] WO 9735966 A1 19971002 - MAXYGEN INC [US], et al
- [Y] CRAMERI A ET AL: "COMBINATORIAL MULTIPLE CASSETTE MUTAGENESIS CREATES ALL THE PERMUTATIONS OF MUTANT AND WILD-TYPE SEQUENCES", BIOTECHNIQUES, vol. 18, no. 2, 1 February 1995 (1995-02-01), pages 194 - 196, XP000489656
- [Y] A. CAMERI ET AL.: "Construction and evolution of antibody-phage libraries by DNA shuffling", NATURE MEDICINE, vol. 2, no. 1, January 1996 (1996-01-01), NATURE PUBLISHING CO., NY, US, pages 100 - 102, XP002098467
- See references of WO 9735957A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9735957 A1 19971002; AU 2337797 A 19971017; AU 729505 B2 20010201; AU 729505 C 20060223; EP 0932670 A1 19990804; EP 0932670 A4 19990804; IL 126191 A0 19990509; JP 2002514901 A 20020521; US 2001046707 A1 20011129; US 2002068363 A1 20020606; US 6096548 A 20000801; US 6358742 B1 20020319; US 6387702 B1 20020514; US 6391552 B2 20020521; US 6482647 B1 20021119
DOCDB simple family (application)
US 9704494 W 19970320; AU 2337797 A 19970320; EP 97916119 A 19970320; IL 12619197 A 19970320; JP 53449797 A 19970320; US 43092799 A 19991101; US 43093199 A 19991101; US 43100399 A 19991101; US 72406700 A 20001128; US 79240997 A 19970203