Title (en)

METHODS AND COMPOSITIONS FOR TREATING URINARY INCONTINENCE USING ENANTIOMERICALLY ENRICHED (R)-TRIDIHEXETHYL

Title (de)

VERFAHREN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON HARNINKONTINENZ MIT ENANTIOMEREN-ANGERREICHTERTEM (R)-TRIDIHEXETHYL

Title (fr)

PROCEDES ET COMPOSITIONS DE TRAITEMENT DE L'INCONTINENCE URINAIRE PAR (R)-TRIDIHEXETHYLE ENRICHI EN ENANTIOMERE

Publication

EP 0933992 A4 20000209 (EN)

Application

EP 97931552 A 19970627

Priority

• US 9711647 W 19970627
• US 2115596 P 19960701

Abstract (en)

[origin: WO9800011A1] A method for treating urinary incontinence, such as incontinence resulting from bladder detrusor muscle instability, using enantiomerically enriched (R)-tridihexethyl. The method comprises administering a therapeutically effective amount of enantiomerically enriched (R)-tridihexethyl or a pharmaceutically acceptable salt thereof, substantially free of the (S)-tridihexethyl enantiomer. Pharmaceutical compositions for the treatment of urinary incontinence comprising enantiomerically enriched (R)-tridihexethyl, or a pharmaceutically acceptable salt thereof, and an acceptable carrier are also disclosed.

IPC 1-7

A61K 31/14; C07C 215/40

IPC 8 full level

A61K 31/14 (2006.01)

CPC (source: EP)

A61K 31/14 (2013.01)

Citation (search report)

• [X] SCHILL, GORAN ET AL: "Chiral separation of cationic drugs on an.alpha.1-acid glycoprotein bonded stationary phase", J. LIQ. CHROMATOGR. (1986), 9(2-3), 641-66, XP000863443
• [A] ARIENS: "STEREOCHEMIE UND PHARMAKOLOGISCHE WIRKUNG", DEUTSCHE APOTHEKER ZEITUNG, vol. 116, no. 24, 1976, pages 851 - 852, XP000863126
• [A] PONS: "parasympathicolytiques", REVUE DU PRACTICIEN, vol. 41, no. 26, 1991, pages 2801 - 2804, XP000863118
• See references of WO 9800011A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9800011 A1 19980108; EP 0933992 A1 19990811; EP 0933992 A4 20000209

DOCDB simple family (application)

US 9711647 W 19970627; EP 97931552 A 19970627