EP 0934410 A1 19990811 - BRAIN-ASSOCIATED INHIBITOR OF TISSUE-TYPE PLASMINOGEN ACTIVATOR
Title (en)
BRAIN-ASSOCIATED INHIBITOR OF TISSUE-TYPE PLASMINOGEN ACTIVATOR
Title (de)
GEHIRN ASSOZIIERTE INHIBITOREN DES GEWEBEPLASMINOGENAKTIVATORS
Title (fr)
INHIBITEUR CEREBRO-ASSOCIE DE L'ACTIVATEUR DU PLASMINOGENE DE TYPE TISSULAIRE
Publication
Application
Priority
US 9616484 W 19961011
Abstract (en)
[origin: WO9816643A1] The present invention relates to a novel BAIT protein which is a member of serpin superfamily which is expressed primarily in brain tissue. In particular, isolated nucleic acid molecules are provided encoding the human BAIT protein. BAIT polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of BAIT activity. Also provided are diagnostic methods for detecting nervous system-related disorders and therapeutic methods for treating nervous system-related disorders.
IPC 1-7
C12N 15/15; C07K 14/81; C12N 1/21; C12N 5/10; C07K 16/38; A61K 38/57
IPC 8 full level
A61K 38/00 (2006.01); A61P 9/00 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); C07K 14/81 (2006.01); C07K 16/38 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/15 (2006.01); C12P 21/02 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); A61P 35/00 (2017.12); A61P 35/04 (2017.12); C07K 14/8121 (2013.01)
Citation (search report)
See references of WO 9816643A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9816643 A1 19980423; AU 7431796 A 19980511; CA 2268007 A1 19980423; EP 0934410 A1 19990811; JP 2002501365 A 20020115
DOCDB simple family (application)
US 9616484 W 19961011; AU 7431796 A 19961011; CA 2268007 A 19961011; EP 96936500 A 19961011; JP 51829398 A 19961011