Global Patent Index - EP 0935464 A1

EP 0935464 A1 19990818 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (en)

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (de)

HEMMER DER FARNESYL-PROTEINTRANSFERASE

Title (fr)

INHIBITEURS DE TRANSFERASE DE FARNESYL-PROTEINE

Publication

EP 0935464 A1 19990818 (EN)

Application

EP 97917129 A 19970331

Priority

  • GB 9613690 A 19960628
  • US 9705237 W 19970331
  • US 1477696 P 19960403

Abstract (en)

[origin: WO9736584A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

IPC 1-7

A61K 31/415; C07D 233/61; C07D 233/64

IPC 8 full level

A61K 31/00 (2006.01); A61K 31/415 (2006.01); A61K 31/4164 (2006.01); A61P 13/00 (2006.01); A61P 13/12 (2006.01); A61P 25/00 (2006.01); A61P 25/02 (2006.01); A61P 27/00 (2006.01); A61P 27/02 (2006.01); A61P 31/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); C07D 233/54 (2006.01); C07D 233/61 (2006.01); C07D 233/64 (2006.01)

CPC (source: EP)

A61P 13/00 (2017.12); A61P 13/12 (2017.12); A61P 25/00 (2017.12); A61P 25/02 (2017.12); A61P 27/00 (2017.12); A61P 27/02 (2017.12); A61P 31/00 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); C07D 233/64 (2013.01)

Citation (search report)

See references of WO 9736584A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9736584 A1 19971009; AU 2555797 A 19971022; AU 706629 B2 19990617; CA 2250937 A1 19971009; EP 0935464 A1 19990818; JP 2000507586 A 20000620

DOCDB simple family (application)

US 9705237 W 19970331; AU 2555797 A 19970331; CA 2250937 A 19970331; EP 97917129 A 19970331; JP 53551197 A 19970331