EP 0935608 A1 19990818 - CYTOTOXIC PEPTIDES
Title (en)
CYTOTOXIC PEPTIDES
Title (de)
CYTOTOXISCHE PEPTIDE
Title (fr)
PEPTIDES CYTOTOXIQUES
Publication
Application
Priority
- AU 9700640 W 19970926
- AU PO265996 A 19960927
- AU PO268096 A 19960930
Abstract (en)
[origin: WO9813377A1] This invention relates to cytotoxic, myristylated peptides derived from the N-terminus of the Nef protein. The peptides preferably comprise a domain comprising a net positive charge and an alpha -helical region. The invention also relates to compounds which inhibit the cytotoxicity of the Nef protein, the methods of preventing Nef toxicity, HIV infection, and to pharmaceutical compositions comprising such compounds.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 38/05 (2006.01); A61K 38/06 (2006.01); A61K 38/07 (2006.01); A61K 38/16 (2006.01); A61K 45/00 (2006.01); A61P 31/18 (2006.01); A61P 43/00 (2006.01); C07K 5/072 (2006.01); C07K 5/087 (2006.01); C07K 5/097 (2006.01); C07K 5/103 (2006.01); C07K 7/06 (2006.01); C07K 14/16 (2006.01); C12Q 1/02 (2006.01); G01N 33/50 (2006.01)
CPC (source: EP)
A61P 31/18 (2017.12); A61P 43/00 (2017.12); C07K 5/06113 (2013.01); C07K 5/0812 (2013.01); C07K 5/0821 (2013.01); C07K 7/06 (2013.01); C07K 14/005 (2013.01); G01N 33/5014 (2013.01); A61K 38/00 (2013.01); C12N 2740/16322 (2013.01); G01N 2333/163 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9813377 A1 19980402; AU 4370897 A 19980417; AU 716098 B2 20000217; CA 2263134 A1 19980402; EP 0935608 A1 19990818; EP 0935608 A4 20040915; JP 2001502897 A 20010306
DOCDB simple family (application)
AU 9700640 W 19970926; AU 4370897 A 19970926; CA 2263134 A 19970926; EP 97941730 A 19970926; JP 51507298 A 19970926