Global Patent Index - EP 0937079 A4

EP 0937079 A4 2001-01-24 - STABILIZED CARBAPENEM ANTIBIOTIC COMPOSITIONS AND METHOD OF MAKING

Title (en)

STABILIZED CARBAPENEM ANTIBIOTIC COMPOSITIONS AND METHOD OF MAKING

Title (de)

STABILISIERTE ANTIBIOTISCHE CARBAPENEM-ZUSAMMENSETZUNGEN UND EINE METHODE ZU IHRER HERSTELLUNG

Title (fr)

COMPOSITIONS ANTIBIOTIQUES STABILISEES A BASE DE CARBAPENEM ET PROCEDE DE PRODUCTION

Publication

EP 0937079 A4 (EN)

Application

EP 97913772 A

Priority

  • GB 9626211 A
  • US 9719336 W
  • US 2952096 P

Abstract (en)

[origin: WO9818800A1] A method is presented for stabilizing carbapenem antibiotics by carboxylating the pyrrolidinyl amino with a carbon dioxide source. The resulting compounds and pharmaceutical compositions thereof can be used in the treatment of infectious diseases, including those resulting from gram positive and negative, aerobic and anaerobic bacteria. The compounds have favorable pharmaceutical properties and stability against beta -lactamases, and a favorable duration of action.

IPC 1-7 (main, further and additional classification)

C07D 487/04; A61K 31/395

IPC 8 full level (invention and additional information)

C07D 477/00 (2006.01); A61K 31/407 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61P 31/04 (2006.01); C07D 477/02 (2006.01); C07D 477/20 (2006.01)

CPC (invention and additional information)

C07D 477/20 (2013.01); C07D 477/02 (2013.01)

Citation (search report)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9818800 A1 19980507; AU 5088198 A 19980522; AU 725298 B2 20001012; CA 2268820 A1 19980507; EP 0937079 A1 19990825; EP 0937079 A4 20010124; JP 2000508343 A 20000704

INPADOC legal status


2004-01-02 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20030628

2003-04-02 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20030217

2001-01-24 [A4] SUPPLEMENTARY SEARCH REPORT

- Ref Legal Event Code: A4

- Effective date: 20001212

2001-01-24 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

1999-08-25 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19990528

1999-08-25 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE