Global Patent Index - EP 0938313 A4

EP 0938313 A4 2000-02-23 - METHODS AND COMPOSITIONS FOR TREATING URINARY INCONTINENCE USING ENANTIOMERICALLY ENRICHED (S)-CLIDINIUM

Title (en)

METHODS AND COMPOSITIONS FOR TREATING URINARY INCONTINENCE USING ENANTIOMERICALLY ENRICHED (S)-CLIDINIUM

Title (de)

VERFAHREN UND ZUSAMMENSTELLUNGEN ZUR BEHANDLUNG VON URININKONTINENZ DURCH ENANTOMERISCH ANGEREICHERTES (S)-CLIDINUM

Title (fr)

PROCEDES ET COMPOSITIONS POUR TRAITER L'INCONTINENCE URINAIRE AVEC DU (S)-CLIDINIUM ENRICHI PAR ENANTIOMORPHISME

Publication

EP 0938313 A4 (EN)

Application

EP 97932350 A

Priority

  • US 9711259 W
  • US 2092596 P

Abstract (en)

[origin: WO9800139A1] A method for treating urinary incontinence, such as incontinence resulting from bladder detrusor muscle instability, using enantiomerically enriched (S)-clidinium. The method comprises administering a therapeutically effective amount of enantiomerically enriched (S)-clidinium, or a pharmaceutically acceptable salt thereof, substantially free of the (R)-clidinium enantiomer. Pharmaceutical compositions for the treatment of urinary incontinence comprising enantiomerically enriched (S)-clidinium, or a pharmaceutically acceptable salt thereof, and an acceptable carrier are also disclosed.

IPC 1-7 (main, further and additional classification)

A61K 31/435; C07D 453/02

IPC 8 full level (invention and additional information)

A61K 31/439 (2006.01); C07D 453/02 (2006.01)

CPC (invention and additional information)

A61K 31/439 (2013.01); C07D 453/02 (2013.01)

Citation (search report)

  • [PX] KOPPENHOEFER, BERNHARD ET AL: "Separation of enantiomers of drugs by capillary electrophoresis Part 4: hydroxypropyl-gamma-cyclodextrin as chiral solvating agent", ELECTROPHORESIS (1997), 18(6), 924-930, XP000863400
  • [PX] LIN, BINGCHENG ET AL: "Investigation of 123 chiral drugs by cyclodextrin-modified capillary electrophoresis", LC-GC (1997), 15(1), 40, 44-46, XP000863469
  • [X] KOPPENHOEFER B. ET AL: "Separation of enantiomers of drugs by capillary electrophoresis I..gamma.-Cyclodextrin as chiral solvating agent.", JOURNAL OF CHROMATOGRAPHY A, (1995) 717/1-2 (181-190)., XP000605057
  • [X] LIN B C (REPRINT) ET AL: "SEPARATION OF DRUG ENANTIOMERS BY CAPILLARY ELECTROPHORESIS ALPHA-CYCLODEXTRIN AS CHIRAL SOLVATING AGENT", CHROMATOGRAPHIA, (JAN 1996) VOL. 42, NO. 1-2, PP. 106-110. ISSN: 0009-5893., vol. 42, no. 1/2, 1996, DALIAN INST CHEM PHYS, ZHONG SHAN RD 161, DALIAN 116012, PEOPLES R CHINA (Reprint);CHINA PHARMACEUT UNIV, NANJING 250009, PEOPLES R CHINA; UNIV TUBINGEN, INST ORGAN CHEM, D-72076 TUBINGEN, GERMANY, pages 106 - 110, XP000863359
  • [A] HAURI D.: "[Incontinence of urine: Possibilities for pharmacotherapy].", MEDIZINISCHE MONATSSCHRIFT FUR PHARMAZEUTEN, (1984) 7/8 (233-239). CODEN: MMPHDB, XP000863460
  • [A] YURDAKOK M ET AL: "Treatment of enuresis: a study with imipramine, amitriptyline, chlordiazepoxide- clidinium and piracetam.", TURKISH JOURNAL OF PEDIATRICS, (1986 JUL-SEP) 28 (3) 171-5., XP000863478
  • See also references of WO 9800139A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9800139 A1 19980108; EP 0938313 A1 19990901; EP 0938313 A4 20000223

INPADOC legal status


2003-08-06 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20030103

2000-02-23 [A4] DESPATCH OF SUPPLEMENTARY SEARCH REPORT

- Effective date: 20000111

2000-02-23 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

1999-09-01 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990120

1999-09-01 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE