EP 0938484 A1 19990901 - 2R,4S,R,R- AND 2S,4R,R,R-HYDROXYITRACONAZOLE
Title (en)
2R,4S,R,R- AND 2S,4R,R,R-HYDROXYITRACONAZOLE
Title (de)
2R,4S,R,R- UND 2S,4R,R,R-HYDROXYITRACONAZOL
Title (fr)
HYDROXY-ITRACONAZOLE 2R,4S,R,R ET 2S,4R,R,R
Publication
Application
Priority
- US 9720462 W 19971112
- US 2999296 P 19961112
Abstract (en)
[origin: WO9821205A1] A method of preparation of optically pure isomers of hydroxyitraconazole, in particular the two cis dioxolane diastereomers of the sec-butyl R,R-isomer, and to phosphate and sulfate derivatives thereof is disclosed. Pharmaceutical compositions containing these compounds and their use for the treatment of fungal infection are also disclosed.
IPC 1-7
IPC 8 full level
C07D 405/14 (2006.01); A61K 31/496 (2006.01); A61P 31/10 (2006.01); C07D 249/12 (2006.01); C07D 405/06 (2006.01); C07D 521/00 (2006.01)
CPC (source: EP)
A61P 31/10 (2017.12); C07D 231/12 (2013.01); C07D 233/56 (2013.01); C07D 249/08 (2013.01); C07D 249/12 (2013.01)
Citation (search report)
See references of WO 9821205A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated extension state (EPC)
AL LT LV MK RO SI
DOCDB simple family (publication)
WO 9821205 A1 19980522; AU 5251398 A 19980603; CA 2269622 A1 19980522; CN 1237173 A 19991201; EP 0938484 A1 19990901; JP 2001504466 A 20010403
DOCDB simple family (application)
US 9720462 W 19971112; AU 5251398 A 19971112; CA 2269622 A 19971112; CN 97199657 A 19971112; EP 97947428 A 19971112; JP 52272598 A 19971112