EP 0939822 A2 19990908 - USE OF MUTATED MACROLIDE BINDING PROTEIN FOR THE PREVENTION OF GUHD
Title (en)
USE OF MUTATED MACROLIDE BINDING PROTEIN FOR THE PREVENTION OF GUHD
Title (de)
VERWENDUNG EINES MUTIERTEN MACROLIDE BINDENDEN PROTEINS ZUR VERHÜTUNG DES GVHDS
Title (fr)
UTILISATION D'UNE PROTEINE DE FIXATION DE MACROLIDE MUTEE POUR PREVENIR LA REACTION DU GREFFON CONTRE L'HOTE
Publication
Application
Priority
- US 9715153 W 19970827
- US 2466696 P 19960827
Abstract (en)
[origin: WO9808956A2] This invention is directed to a modified cyclosporin A and to a modified, genetically engineered version of its receptor, cyclophilin. This invention is further directed to a method for treating host versus graft disease following blood marrow transplantation by transfecting stem cells so that after introduction into a patient the stem cells will express the modified cyclophilin, and, as necessary, administer the modified cyclosporin A to the patient.
IPC 1-7
C12N 15/54; C12N 15/12; C12N 5/10; C12N 9/12; C07K 14/715; A61K 48/00; A01K 67/027
IPC 8 full level
C12N 15/09 (2006.01); A01K 67/027 (2006.01); A61K 31/35 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 7/00 (2006.01); A61P 37/00 (2006.01); C07K 7/64 (2006.01); C07K 14/47 (2006.01); C07K 14/715 (2006.01); C12N 5/10 (2006.01); C12N 9/16 (2006.01); C12N 9/90 (2006.01); C12N 15/54 (2006.01)
CPC (source: EP)
A01K 67/0271 (2013.01); A61P 7/00 (2017.12); A61P 37/00 (2017.12); C07K 7/645 (2013.01); C07K 14/715 (2013.01); C12N 9/16 (2013.01); C12N 9/90 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 9808956A2
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9808956 A2 19980305; WO 9808956 A3 19980618; AU 4167297 A 19980319; CA 2263951 A1 19980305; EP 0939822 A2 19990908; JP 2001527384 A 20011225
DOCDB simple family (application)
US 9715153 W 19970827; AU 4167297 A 19970827; CA 2263951 A 19970827; EP 97939629 A 19970827; JP 51190498 A 19970827