EP 0941243 A1 19990915 - POLYPEPTIDES COMPRISING GAX PROTEIN DOMAINS, INVOLVED IN REPRESSING TRANSCRIPTION AND/OR INTERACTING WITH OTHER PROTEINS, CORRESPONDING NUCLEIC ACIDS AND THEIR USE
Title (en)
POLYPEPTIDES COMPRISING GAX PROTEIN DOMAINS, INVOLVED IN REPRESSING TRANSCRIPTION AND/OR INTERACTING WITH OTHER PROTEINS, CORRESPONDING NUCLEIC ACIDS AND THEIR USE
Title (de)
POLYPEPTIDE, WELCHE DOMÄNEN DES PROTEINGAX ENTHALTEN, DIE EINE ROLLE BEI DER REPRESSION DER TRANSKRIPTEN SPIELEN BZW. MIT ANDEREN PROTEINEN INTERAGIEREN, SOWIE DEREN NUKLEINSÄUREN UND VERWENDUNG
Title (fr)
POLYPEPTIDES COMPRENANT DES DOMAINES DE LA PROTEINE GAX, IMPLIQUES DANS LA REPRESSION DE TRANSCRIPTION ET/OU INTERAGISSANT AVEC D'AUTRES PROTEINES, ACIDES NUCLEIQUES CORRESPONDANTS ET LEURS UTILISATIONS
Publication
Application
Priority
- FR 9701850 W 19971016
- FR 9612730 A 19961018
Abstract (en)
[origin: US6121005A] This invention pertains to polynucleotides comprising GAX domains involved in GAX biological activity. It may pertain, notably, to domains involved in the interaction of GAX with other molecules or domains that are responsible for biological activity. The invention also pertains to chimeric molecules comprising a GAX functional domain. It also pertains to the use of GAX to repress gene expression, as well as the use of compounds that inhibit GAX interaction with certain cellular partners to modulate GAX activity. It also pertains to a method for screening and/or identifying GAX cellular partners.
IPC 1-7
C07K 14/47; C12N 15/12; C12N 15/86; C12N 15/62; A61K 38/17; G01N 33/50
IPC 8 full level
G01N 33/50 (2006.01); A61K 31/711 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61K 38/18 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 9/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07K 14/00 (2006.01); C07K 14/47 (2006.01); C07K 14/515 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12N 15/62 (2006.01); C12N 15/86 (2006.01); G01N 33/15 (2006.01); G01N 33/53 (2006.01)
IPC 8 main group level
A61K (2006.01); C07H (2006.01); C07K (2006.01); C12N (2006.01); C12Q (2006.01); G01N (2006.01)
CPC (source: EP KR US)
A61P 9/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07K 14/00 (2013.01 - KR); C07K 14/4703 (2013.01 - EP US); C07K 2319/00 (2013.01 - EP US); G01N 2500/04 (2013.01 - EP US); Y10S 977/80 (2013.01 - EP US); Y10S 977/915 (2013.01 - EP US)
Citation (search report)
See references of WO 9817686A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
US 6121005 A 20000919; AP 9901510 A0 19990630; AU 4871397 A 19980515; AU 741586 B2 20011206; BG 103342 A 20000531; BG 63548 B1 20020430; BR 9711947 A 19990824; CA 2268045 A1 19980430; CN 1237980 A 19991208; CZ 131899 A3 19990714; EA 003694 B1 20030828; EA 199900387 A1 19991028; EP 0941243 A1 19990915; FR 2754822 A1 19980424; FR 2754822 B1 19981127; HU P9903956 A2 20000328; HU P9903956 A3 20020128; IL 129478 A0 20000229; JP 2001503615 A 20010321; KR 20000049249 A 20000725; NO 991830 D0 19990416; NO 991830 L 19990616; NZ 335283 A 20010223; OA 11034 A 20030306; PL 332874 A1 19991025; SK 51199 A3 20000410; WO 9817686 A1 19980430; ZA 979390 B 19980512
DOCDB simple family (application)
US 95086097 A 19971015; AP 9901510 A 19971016; AU 4871397 A 19971016; BG 10334299 A 19990416; BR 9711947 A 19971016; CA 2268045 A 19971016; CN 97199823 A 19971016; CZ 131899 A 19971016; EA 199900387 A 19971016; EP 97911277 A 19971016; FR 9612730 A 19961018; FR 9701850 W 19971016; HU P9903956 A 19971016; IL 12947897 A 19971016; JP 51902498 A 19971016; KR 19997003354 A 19990416; NO 991830 A 19990416; NZ 33528397 A 19971016; OA 9900083 A 19990416; PL 33287497 A 19971016; SK 51199 A 19971016; ZA 979390 A 19971020