EP 0941355 A1 19990915 - RECOMBINANT BICISTRON ADENOVIRUS FOR TREATING PATHOLOGICAL CONDITIONS LINKED WITH DYSLIPOPROTEINEMIA
Title (en)
RECOMBINANT BICISTRON ADENOVIRUS FOR TREATING PATHOLOGICAL CONDITIONS LINKED WITH DYSLIPOPROTEINEMIA
Title (de)
REKOMBINANTE BICISTRONISCHE ADENOVIREN ZUR BEHANDLUNG VON MIT DYSLIPOPROTEINÄMIEN GEBUNDENEN KRANKHEITEN
Title (fr)
ADENOVIRUS RECOMBINANTS BICISTRONIQUES POUR LE TRAITEMENT DE PATHOLOGIES LIEES AUX DYSLIPOPROTEINEMIES
Publication
Application
Priority
- FR 9702043 W 19971113
- FR 9613969 A 19961115
Abstract (en)
[origin: FR2755975A1] The invention concerns a defective recombinant virus and preferably an adenovirus characterised in that it comprises at least two nucleic acids coding for distinct enzymes, proteins and/or co-factors involved in the reverse transfer of cholesterol, said nucleic acids being operationally bound to a transcriptional promoter and mutually separated by a sequence coding for an internal entry site of the IRES ribosome. The invention further concerns plasmid constructs useful for preparing these adenovirus, and cells transformed by these plasmids or adenovirus and pharmaceutical compositions containing said adenovirus.
IPC 1-7
IPC 8 full level
A61K 48/00 (2006.01); A61P 7/00 (2006.01); A61P 9/10 (2006.01); C07K 14/435 (2006.01); C07K 14/47 (2006.01); C12N 15/09 (2006.01); C12N 1/21 (2006.01); C12N 7/00 (2006.01); C12N 7/01 (2006.01); C12N 9/10 (2006.01); C12N 9/20 (2006.01); C12N 15/62 (2006.01); C12N 15/86 (2006.01); C12N 15/861 (2006.01)
CPC (source: EP KR)
A61K 48/00 (2013.01 - KR); A61P 7/00 (2018.01 - EP); A61P 9/10 (2018.01 - EP); C07K 14/47 (2013.01 - EP); C12N 9/1029 (2013.01 - EP); C12N 9/20 (2013.01 - EP); C12N 15/62 (2013.01 - KR); C12N 15/86 (2013.01 - EP KR); A61K 48/00 (2013.01 - EP); C12N 2710/10343 (2013.01 - EP); C12N 2830/42 (2013.01 - EP); C12N 2840/203 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
FR 2755975 A1 19980522; FR 2755975 B1 19990507; AU 5125298 A 19980610; AU 721654 B2 20000713; BR 9712957 A 20000201; CA 2271437 A1 19980528; CZ 170399 A3 19990811; EP 0941355 A1 19990915; HU P9904500 A2 20000528; HU P9904500 A3 20020128; IL 129823 A0 20000229; JP 2001506488 A 20010522; KR 20000053320 A 20000825; NO 992260 D0 19990510; NO 992260 L 19990510; SK 63499 A3 20000516; WO 9822606 A1 19980528; ZA 9710271 B 19980821
DOCDB simple family (application)
FR 9613969 A 19961115; AU 5125298 A 19971113; BR 9712957 A 19971113; CA 2271437 A 19971113; CZ 170399 A 19971113; EP 97945922 A 19971113; FR 9702043 W 19971113; HU P9904500 A 19971113; IL 12982397 A 19971113; JP 52326398 A 19971113; KR 19997004322 A 19990515; NO 992260 A 19990510; SK 63499 A 19971113; ZA 9710271 A 19971113