EP 0942910 A1 19990922 - 1,4-DIAZABICYCLO¬2.2.2 OCT-2-YLMETHYL DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATION
Title (en)
1,4-DIAZABICYCLO¬2.2.2 OCT-2-YLMETHYL DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATION
Title (de)
1,4-DIAZABICYCLO¬2.2.2 OCT2-YLMETHYL BENZOATDERIVATE, IHRE HERSTELLUNG UND THERAPEUTISCHE VERWENDUNG
Title (fr)
DERIVES DE BENZOATE DE 1,4-DIAZABICYCLO¬2.2.2 OCT-2-YLMETHYLE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
Publication
Application
Priority
- FR 9702174 W 19971202
- FR 9614847 A 19961204
Abstract (en)
[origin: US6057321A] PCT No. PCT/FR97/02174 Sec. 371 Date Jun. 4, 1999 Sec. 102(e) Date Jun. 4, 1999 PCT Filed Dec. 2, 1997 PCT Pub. No. WO98/24790 PCT Pub. Date Jun. 11, 1998The invention concerns compounds of general formula (I) in which R1 represents a methyl group, X1 represents a hydrogen atom, or OR1 and X1 together form a group of formula -O(CH2)2 -,-O(CH2)3-, -O(CH2)2O- or -O(CH2)3O-, X2 represents a hydrogen atom or an amino group, and X3 representing a halogen atom. The compounds are ligands of serotoninergic receptors of the 5-HT3 and/or 5-HT4 types, and act as 5-HT4 agonists and/or 5-HT3 antogonists.
IPC 1-7
IPC 8 full level
A61K 31/4995 (2006.01); A61P 1/00 (2006.01); A61P 1/08 (2006.01); A61P 9/00 (2006.01); A61P 13/00 (2006.01); A61P 25/00 (2006.01); A61P 25/06 (2006.01); A61P 25/18 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); A61P 43/00 (2006.01); C07D 487/08 (2006.01)
CPC (source: EP KR US)
A61P 1/00 (2017.12 - EP); A61P 1/08 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 13/00 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/06 (2017.12 - EP); A61P 25/18 (2017.12 - EP); A61P 25/22 (2017.12 - EP); A61P 25/24 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 487/08 (2013.01 - EP KR US)
Citation (search report)
See references of WO 9824790A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated extension state (EPC)
AL LT LV MK RO SI
DOCDB simple family (publication)
US 6057321 A 20000502; AU 7624598 A 19980629; BG 103432 A 20000630; BR 9714215 A 20000418; CA 2271072 A1 19980611; CN 1239962 A 19991229; CZ 193799 A3 19990915; EE 9900218 A 19991215; EP 0942910 A1 19990922; FR 2756563 A1 19980605; FR 2756563 B1 19981224; HU P9904206 A2 20000628; HU P9904206 A3 20000728; IL 129927 A0 20000229; JP 2001504855 A 20010410; KR 20000069283 A 20001125; NO 992676 D0 19990602; NO 992676 L 19990729; NZ 336044 A 20000327; SK 74199 A3 20000214; TR 199901068 T2 19990721; WO 9824790 A1 19980611
DOCDB simple family (application)
US 31941399 A 19990604; AU 7624598 A 19971202; BG 10343299 A 19990526; BR 9714215 A 19971202; CA 2271072 A 19971202; CN 97180353 A 19971202; CZ 193799 A 19971202; EE 9900218 A 19971202; EP 97948976 A 19971202; FR 9614847 A 19961204; FR 9702174 W 19971202; HU P9904206 A 19971202; IL 12992797 A 19971202; JP 52527298 A 19971202; KR 19997004915 A 19990603; NO 992676 A 19990602; NZ 33604497 A 19971202; SK 74199 A 19971202; TR 9901068 T 19971202