Global Patent Index - EP 0944388 A2

EP 0944388 A2 19990929 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (en)

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (de)

HEMMERN VON FARNESYL PROTEIN TRANSFERASE

Title (fr)

INHIBITEURS DE LA FARNESYL-PROTEINE TRANSFERASE

Publication

EP 0944388 A2 19990929 (EN)

Application

EP 97921256 A 19970327

Priority

  • GB 9609981 A 19960513
  • US 9706487 W 19970327
  • US 1479196 P 19960403

Abstract (en)

[origin: WO9738665A2] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

IPC 1-7

A61K 31/445; C07D 401/04; C07D 401/06; C07D 401/12

IPC 8 full level

A61K 31/445 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/4709 (2006.01); A61P 9/00 (2006.01); A61P 13/12 (2006.01); A61P 27/02 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 211/62 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01)

CPC (source: EP)

A61P 9/00 (2017.12); A61P 13/12 (2017.12); A61P 27/02 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07D 211/62 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 413/14 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9738665 A2 19971023; WO 9738665 A3 19971127; AU 2734797 A 19971107; AU 715202 B2 20000120; CA 2249601 A1 19971023; EP 0944388 A2 19990929; EP 0944388 A4 20010816; JP 2001519766 A 20011023

DOCDB simple family (application)

US 9706487 W 19970327; AU 2734797 A 19970327; CA 2249601 A 19970327; EP 97921256 A 19970327; JP 53738897 A 19970327