Global Patent Index - EP 0944594 A4

EP 0944594 A4 2000-05-03 - INHIBITORS OF THE ENZYMATIC ACTIVITY OF PSA

Title (en)

INHIBITORS OF THE ENZYMATIC ACTIVITY OF PSA

Title (de)

INHIBITOREN DER ENZYMATISCHEN AKTIVIÄT VON PSA

Title (fr)

INHIBITEURS DE L'ACTIVITE ENZYMATIQUE DE L'ANTIGENE PSA

Publication

EP 0944594 A4 (EN)

Application

EP 97952334 A

Priority

  • US 9722573 W
  • US 3317996 P
  • US 4054397 P
  • US 4036297 P
  • US 4403297 P
  • US 4053997 P
  • US 4080497 P
  • US 4080597 P
  • US 4705497 P
  • US 4705597 P
  • US 5072197 P

Abstract (en)

[origin: WO9825895A1] This invention is directed to novel azetidinone compounds, to certain intermediates and processes for preparing these azetidinone compounds, and to formulations containing the same. The present invention also relates to the use of these azetidinones as inhibitors of the enzymatic activity of Prostate-Specific Antigen (PSA) as well as for treating prostatic cancer (Pca), Pca metastasis, benign prostatic hyperplasia (BPH) and breast cancer (Bc). Another aspect of the invention relates to inventive methods for treating Pca, Pca metastasis, BPH and Bc by administering any PSA inhibiting compound.

IPC 1-7 (main, further and additional classification)

C07D 205/04; A61K 31/43; A61K 31/545; C07D 205/08

IPC 8 full level (invention and additional information)

A61K 31/00 (2006.01); A61K 31/397 (2006.01); A61K 31/4035 (2006.01); A61K 31/422 (2006.01); A61K 31/423 (2006.01); A61K 31/427 (2006.01); A61K 31/4427 (2006.01); A61K 31/4439 (2006.01); A61K 31/4709 (2006.01); A61K 31/506 (2006.01); A61K 31/517 (2006.01); A61K 31/53 (2006.01); A61P 13/08 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); A61P 43/00 (2006.01); C07D 205/08 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01)

CPC (invention and additional information)

C07D 401/14 (2013.01); A61K 31/00 (2013.01); A61K 31/397 (2013.01); A61K 31/4035 (2013.01); A61K 31/422 (2013.01); A61K 31/4439 (2013.01); C07D 205/08 (2013.01); C07D 403/04 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01)

Citation (search report)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9825895 A1 19980618; AU 5597098 A 19980703; BR 9714394 A 20000516; CA 2274958 A1 19980618; EP 0944594 A1 19990929; EP 0944594 A4 20000503; HU 0000288 A2 20010129; HU 0000288 A3 20010428; IL 130300 D0 20000601; JP 2002514197 A 20020514; KR 20000069431 A 20001125

INPADOC legal status


2002-01-30 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20010726

2001-05-02 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010315

2000-05-03 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20000316

2000-05-03 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

1999-09-29 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990609

1999-09-29 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

1999-09-29 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: AL PAYMENT 19990609;LT PAYMENT 19990609;LV PAYMENT 19990609;RO PAYMENT 19990609;SI PAYMENT 19990609