EP 0944594 A4 20000503 - INHIBITORS OF THE ENZYMATIC ACTIVITY OF PSA
Title (en)
INHIBITORS OF THE ENZYMATIC ACTIVITY OF PSA
Title (de)
INHIBITOREN DER ENZYMATISCHEN AKTIVIÄT VON PSA
Title (fr)
INHIBITEURS DE L'ACTIVITE ENZYMATIQUE DE L'ANTIGENE PSA
Publication
Application
Priority
- US 9722573 W 19971209
- US 3317996 P 19961213
- US 4054397 P 19970313
- US 4036297 P 19970313
- US 4403297 P 19970313
- US 4053997 P 19970313
- US 4080497 P 19970318
- US 4080597 P 19970318
- US 4705497 P 19970519
- US 4705597 P 19970519
- US 5072197 P 19970625
Abstract (en)
[origin: WO9825895A1] This invention is directed to novel azetidinone compounds, to certain intermediates and processes for preparing these azetidinone compounds, and to formulations containing the same. The present invention also relates to the use of these azetidinones as inhibitors of the enzymatic activity of Prostate-Specific Antigen (PSA) as well as for treating prostatic cancer (Pca), Pca metastasis, benign prostatic hyperplasia (BPH) and breast cancer (Bc). Another aspect of the invention relates to inventive methods for treating Pca, Pca metastasis, BPH and Bc by administering any PSA inhibiting compound.
IPC 1-7
IPC 8 full level
A61K 31/00 (2006.01); A61K 31/397 (2006.01); A61K 31/4035 (2006.01); A61K 31/422 (2006.01); A61K 31/423 (2006.01); A61K 31/427 (2006.01); A61K 31/4427 (2006.01); A61K 31/4439 (2006.01); A61K 31/4709 (2006.01); A61K 31/506 (2006.01); A61K 31/517 (2006.01); A61K 31/53 (2006.01); A61P 13/08 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); A61P 43/00 (2006.01); C07D 205/08 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01)
CPC (source: EP KR)
A61K 31/00 (2013.01 - EP); A61K 31/397 (2013.01 - EP); A61K 31/4035 (2013.01 - EP); A61K 31/422 (2013.01 - EP); A61K 31/4439 (2013.01 - EP); A61P 13/08 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 35/04 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 205/04 (2013.01 - KR); C07D 205/08 (2013.01 - EP); C07D 401/14 (2013.01 - EP); C07D 403/04 (2013.01 - EP); C07D 413/04 (2013.01 - EP); C07D 413/14 (2013.01 - EP)
Citation (search report)
[A] WO 9418164 A1 19940818 - UNIV NEW YORK STATE RES FOUND [US]
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9825895 A1 19980618; AU 5597098 A 19980703; BR 9714394 A 20000516; CA 2274958 A1 19980618; EP 0944594 A1 19990929; EP 0944594 A4 20000503; HU P0000288 A2 20010129; HU P0000288 A3 20010428; IL 130300 A0 20000601; JP 2002514197 A 20020514; KR 20000069431 A 20001125
DOCDB simple family (application)
US 9722573 W 19971209; AU 5597098 A 19971209; BR 9714394 A 19971209; CA 2274958 A 19971209; EP 97952334 A 19971209; HU P0000288 A 19971209; IL 13030097 A 19971209; JP 52690098 A 19971209; KR 19997005218 A 19990611