Global patent index - EP 0946267 A4

EP 0946267 A4 2000-01-05 - MULTIPOLE ION GUIDE ION TRAP MASS SPECTROMETRY

Title (en)

MULTIPOLE ION GUIDE ION TRAP MASS SPECTROMETRY

Title (de)

MULTIPOL IONENLEITER, IONENFALLE MASSENSPEKTROMETRIE

Title (fr)

SPECTROMETRIE A PIEGEAGE D'IONS PAR GUIDE D'IONS MULTIPOLAIRES

Publication

EP 0946267 A4 (EN)

Application

EP 97939401 A

Priority

  • US 9714203 W
  • US 69454296 A

Abstract (en)

[origin: WO9806481A1] A Time-Of-Flight mass analyzer includes a multipole ion guide (16) located in the ion flight path between the ion source (1) and the flight tube (42) of the Time-Of-Flight mass analyzer. In one preferred embodiment, a Time-Of-Flight (TOF) mass analyzer is configured such that a multipole ion guide is positioned in the ion path between the ion source and the ion pulsing region (30) of the TOF mass analyzer. The multiple ion guide electronics and the ion guide entrance and exit electrostatic lenses (26, 27 and 28) are configured to enable the trapping or passing through of ions delivered from an atmospheric pressure ion source. The ion guide electronics can be set to select the mass to charge (m/z) range of ions which can be successfully transmitted or trapped in the ion guide. All or a portion of the ions with stable ion guide trajectories in transmission or trapping mode can then undergo Collisional Induced Dissociation (CID) using one of at least three techniques. The multipole ion guide is used for ion transmission, trapping and fragmentation can reside in one vacuum pumping stage (138) or can extend continuously into more than one vacuum pumping stage (18, 19).

IPC 1-7 (main, further and additional classification)

H01J 49/42; H01J 49/34; H01J 49/40

IPC 8 full level (invention and additional information)

G01N 27/62 (2006.01); B01D 59/44 (2006.01); H01J 49/06 (2006.01); H01J 49/40 (2006.01); H01J 49/42 (2006.01)

CPC (invention and additional information)

H01J 49/40 (2013.01); H01J 49/004 (2013.01); H01J 49/063 (2013.01)

Citation (search report)

  • [A] US 5420425 A
  • [A] DE 19511333 C1
  • [X] GLISH ET AL: "Tandem Quadrupole/Time-of-Flight Instrument for Mass Spectromety/Mass Spectrometry", ANAL.CHEM. (USA), ANALYTICAL CHEMISTRY, vol. 56, no. 13, 13 November 1984 (1984-11-13), pages 2291-2295, XP002120797
  • See also references of WO 9806481A1

Designated contracting state (EPC)

CH DE DK FR GB IT LI SE

EPO simple patent family

WO 9806481 A1 19980219; AU 4149797 A 19980306; CA 2262627 A1 19980219; CA 2262627 C 20070710; CA 2566919 A1 19980219; CA 2566919 C 20110503; EP 0946267 A1 19991006; EP 0946267 A4 20000105; EP 0946267 B1 20110706; EP 0946267 B2 20150812; JP 2001500305 A 20010109; US 6011259 A 20000104

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- Inventor name: ANDRIEN, BRUCE A.

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- Inventor name: DRESCH, THOMAS

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- Inventor name: WHITEHOUSE, CRAIG M.

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