EP 0954260 A1 19991110 - COMPOSITIONS, METHODS AND DEVICES FOR THE TRANSDERMAL DELIVERY OF DRUGS
Title (en)
COMPOSITIONS, METHODS AND DEVICES FOR THE TRANSDERMAL DELIVERY OF DRUGS
Title (de)
ZUSAMMENSETZUNGEN, VERFAHREN UND GERÄTE ZUR TRANSDERMALEN VERABREICHUNG VON ARZNEIMITTELN
Title (fr)
COMPOSITIONS, PROCEDES ET DISPOSITIFS D'ADMINISTRATION TRANSDERMIQUE DE MEDICAMENTS
Publication
Application
Priority
- US 9708636 W 19970522
- US 65228096 A 19960522
Abstract (en)
[origin: WO9743989A1] The present invention is directed to compositions, and methods for the delivery of drugs. Devices for the transdermal delivery of drugs are also provided. Specifically, the present invention relates to hydrogel compositions comprising water and a base mixture, in which the base mixture comprises: (i) a gelling agent consisting of methylcellulose or at least one natural gum, or a mixture thereof; (ii) at least one natural gum; (iii) glucose; (iv) propylparaben; (v) methyl paraben; and (vi) sodium chloride. The compositions may further comprise pectin, glycolic, alcoholic or oil-based additives, a coloring, fragrance, or other pharmaceutically acceptable additive. The compositions may further comprise substituted ureas of the formula R-NH-CO-NH2 such as butylurea. The compositions may further comprise drugs such as hormones selected from progesterone, progestin, estrogen and testosterone. Methods for the treatment of disorders responsive to hormone therapy are also provided. The figure is a cross-sectional view of a membrane-moderated transdermal drug delivery system.
IPC 1-7
IPC 8 full level
A61F 6/06 (2006.01); A61K 9/70 (2006.01); A61K 47/02 (2006.01); A61K 47/26 (2006.01); A61K 47/30 (2006.01); A61K 47/36 (2006.01); A61K 47/38 (2006.01); A61K 47/14 (2006.01)
CPC (source: EP)
A61F 6/06 (2013.01); A61K 9/7023 (2013.01); A61K 47/36 (2013.01); A61K 47/38 (2013.01); A61K 47/02 (2013.01); A61K 47/14 (2013.01); A61K 47/26 (2013.01)
Citation (search report)
See references of WO 9743989A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9743989 A1 19971127; AU 3136897 A 19971209; CA 2256365 A1 19971127; EP 0954260 A1 19991110; IL 127189 A0 19990922; JP 2000513336 A 20001010; US 6214374 B1 20010410
DOCDB simple family (application)
US 9708636 W 19970522; AU 3136897 A 19970522; CA 2256365 A 19970522; EP 97926655 A 19970522; IL 12718997 A 19970522; JP 54269697 A 19970522; US 65228096 A 19960522