EP 0960102 A1 19991201 - AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN
Title (en)
AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN
Title (de)
AMIDINOINDOLE, AMIDINOAZOLE UND ANALOGE DAVON ALS INHIBITOREN VON THROMBIN UND VON FAKTOR XA
Title (fr)
AMIDINOINDOLES, AMIDINOAZOLES ET LEURS ANALOGUES AGISSANT EN TANT QU'INHIBITEURS DU FACTEUR Xa ET DE LA THROMBINE
Publication
Application
Priority
- US 9711325 W 19970630
- US 67676696 A 19960708
- US 4951997 P 19970613
Abstract (en)
[origin: WO9801428A1] The present application describes amidinoindoles, amidinoazoles, and analogs thereof of formula (I): wherein W, W<1>, W<2>, and W<3> are selected from CH and N, provided that one of W<1> and W<2> is C(C(=NH)NH2) and at most two of W, W<1>, W<2>, and W<3> are N and one of J<a> and J<b> is substituted by -(CH2)n-Z-A-B, which are useful as inhibitors of factor Xa or thrombin.
IPC 1-7
C07D 235/06; A61K 31/395; C07D 403/10; C07D 471/04; C07D 401/06; C07D 209/08; C07D 209/16; C07D 401/12; C07D 209/14; C07D 231/12; C07D 231/56
IPC 8 full level
A61K 31/404 (2006.01); A61K 31/41 (2006.01); A61K 31/416 (2006.01); A61K 31/4184 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61P 7/02 (2006.01); A61P 43/00 (2006.01); C07D 209/08 (2006.01); C07D 209/14 (2006.01); C07D 209/16 (2006.01); C07D 209/18 (2006.01); C07D 231/12 (2006.01); C07D 231/56 (2006.01); C07D 235/06 (2006.01); C07D 307/79 (2006.01); C07D 333/58 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 403/06 (2006.01); C07D 403/10 (2006.01); C07D 403/12 (2006.01); C07D 405/14 (2006.01); C07D 471/04 (2006.01)
CPC (source: EP)
A61P 7/02 (2017.12); A61P 43/00 (2017.12); C07D 209/18 (2013.01); C07D 231/56 (2013.01); C07D 235/06 (2013.01); C07D 307/79 (2013.01); C07D 333/58 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 463/06 (2013.01); C07D 471/04 (2013.01)
Citation (search report)
See references of WO 9801428A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9801428 A1 19980115; AU 3645697 A 19980202; CA 2259573 A1 19980115; EP 0960102 A1 19991201; IL 127873 A0 19991028; JP 2002514162 A 20020514; NZ 333696 A 20000623
DOCDB simple family (application)
US 9711325 W 19970630; AU 3645697 A 19970630; CA 2259573 A 19970630; EP 97933214 A 19970630; IL 12787397 A 19970630; JP 50524998 A 19970630; NZ 33369697 A 19970630