EP 0963372 A1 19991215 - 5-AMINOALKOXY-1,4-DIHYDROQUINOXALINE-2,3-DIONES BEING DOPAMINE AGONISTS
Title (en)
5-AMINOALKOXY-1,4-DIHYDROQUINOXALINE-2,3-DIONES BEING DOPAMINE AGONISTS
Title (de)
5-AMINOALKOXY-1,4-DIHYDROCHINOXALIN-2,3-DIONE ALS DOPAMIN AGONSISTEN
Title (fr)
5-AMINOALCOXY-1,4-DIHYDROQUINOXALINE-2,3-DIONES EN TANT QU'AGONISTES DE LA DOPAMINE
Publication
Application
Priority
- US 9801170 W 19980113
- US 80132497 A 19970218
Abstract (en)
[origin: WO9835948A1] This invention relates to compounds of Formula (I) wherein: R<1> and R<2> are independently selected from hydrogen, straight-chain and branched alkyl group having up to 10 carbon atoms or -(CH2)mAr where Ar is phenyl, naphthyl or thienyl, each optionally substituted by one or two substituents selected independently from C1-C6 alkyl, halogen, C1-C6 alkoxide and trifluoromethyl; or NR<1>R<2> is 1,2,3,4-tetrahydroquinolin-1-yl or 1,2,3,4-tetrahydroisoquinolin-2-yl; m is 1-5; n is 1 or 2; Y is halogen, C1-C6 alkyl, and C1-C6 alkoxy; or the pharmaceutically acceptalbe salts thereof, which are dopamine D2 agonists and therefore useful in the treatment of psychoses and Parkinson's disease.
IPC 1-7
IPC 8 full level
A61K 31/502 (2006.01); A61P 25/16 (2006.01); A61P 25/18 (2006.01); A61P 43/00 (2006.01); C07D 241/44 (2006.01); C07D 401/12 (2006.01)
CPC (source: EP KR)
A61P 25/16 (2018.01 - EP); A61P 25/18 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 241/44 (2013.01 - EP KR); C07D 401/12 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9835948 A1 19980820; AR 011669 A1 20000830; AU 6035098 A 19980908; AU 722616 B2 20000810; BR 9807230 A 20000425; CA 2278757 A1 19980820; CN 1248249 A 20000322; EP 0963372 A1 19991215; HU P0001311 A2 20010528; HU P0001311 A3 20010730; IL 131160 A0 20010128; JP 2001511805 A 20010814; KR 20000071162 A 20001125; NZ 336971 A 20001027; TW 434230 B 20010516; ZA 981306 B 19990817
DOCDB simple family (application)
US 9801170 W 19980113; AR P980100618 A 19980211; AU 6035098 A 19980113; BR 9807230 A 19980113; CA 2278757 A 19980113; CN 98802636 A 19980113; EP 98903628 A 19980113; HU P0001311 A 19980113; IL 13116098 A 19980113; JP 53574298 A 19980113; KR 19997007452 A 19990817; NZ 33697198 A 19980113; TW 87101493 A 19980205; ZA 981306 A 19980217