EP 0964694 A1 19991222 - MUCIN-MEDIATED IMMUNOMODULATION
Title (en)
MUCIN-MEDIATED IMMUNOMODULATION
Title (de)
MUCIN-VERMITTELTE IMMUNOMODULATION
Title (fr)
IMMUNOMODULATION INDUITE PAR LA MUCINE
Publication
Application
Priority
- US 9719784 W 19971024
- US 73826296 A 19961025
Abstract (en)
[origin: WO9817300A1] Disclosed is a method of decreasing or preventing the deleterious effects of cytotoxic T lymphocytes that involves identifying an animal having a non-tumor cell at risk of attack by the animal's cytotoxic T lymphocytes, and providing to the cell a molecule having at least one tandem repeat segment of a mucin. Also disclosed is a method of augmenting the immune response against a tumor cell expressing a mucin, using a composition that binds to the tandem repeat segment of the mucin and blocks the CTL-inhibiting effects of the mucin.
IPC 1-7
IPC 8 full level
A01K 67/027 (2006.01); A61K 31/711 (2006.01); A61K 35/26 (2006.01); A61K 35/37 (2006.01); A61K 38/00 (2006.01); A61K 38/17 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); A61P 37/04 (2006.01); A61P 37/06 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01)
CPC (source: EP)
A61K 38/1709 (2013.01); A61P 35/00 (2017.12); A61P 37/04 (2017.12); A61P 37/06 (2017.12); C07K 14/4727 (2013.01); A01K 2217/05 (2013.01); A61K 48/00 (2013.01)
Designated contracting state (EPC)
CH DE GB LI
DOCDB simple family (publication)
WO 9817300 A1 19980430; CA 2269349 A1 19980430; EP 0964694 A1 19991222; EP 0964694 A4 20000913; JP 2001502907 A 20010306
DOCDB simple family (application)
US 9719784 W 19971024; CA 2269349 A 19971024; EP 97946409 A 19971024; JP 51974898 A 19971024