EP 0966469 A1 19991229 - METHOD FOR PRODUCING HETEROAROMATIC ALCOHOLS FREE OF ENANTIOMERS
Title (en)
METHOD FOR PRODUCING HETEROAROMATIC ALCOHOLS FREE OF ENANTIOMERS
Title (de)
VERFAHREN ZUR HERSTELLUNG VON ENANTIOMERENREINEN HETEROATOMATISCHEN ALKOHOLEN
Title (fr)
PROCEDE DE PRODUCTION D'ALCOOLS HETEROAROMATIQUES EXEMPTS D'ENANTIOMERES
Publication
Application
Priority
- DE 19706336 A 19970219
- EP 9800707 W 19980209
Abstract (en)
[origin: DE19706336A1] The invention relates to a method for producing enantiomer-free alcohols of formula (I), where the substituents represent the following: R<1> is a hydrogen or a substituted or unsubstituted C1-C6-alkyl-, C1-C6-alkoxy-, or C1-C6-alkanoyl-; R<2> and R<3> independently of each other represent hydrogen or a substituted or unsubstituted C1-C6-alkyl-, C1-C6-alkoxy-, C1-C6-alkanoyl, C1-C6-alkylthio-, C1-C6-alkyl sulfinyl or C1-C6-alkyl sulfonyl-; and R<4> is not equal R<5> and independently of each other they represent either hydrogen or a substituted or unsubstituted C1-C6-alkyl-, or together with the hydrogen atoms to which they are bound form a substituted or unsubstituted C3-C6-cyclo alkylidene. The method is characterized in that racemic compounds of the formula (II), in which the substituents R<1> to R<5> have the meanings given above and R<6> is a substituted or unsubstituted aryl-, C1-C20-alkyl-, C3-C20-alkenyl-, C3-C20-alkynyl-, are reacted with a lipase or esterase in the presence of an alcohol of the formula R<7>OH (III), where R<7> is a substituted or unsubstituted C1-C10-alkyl-.
IPC 1-7
IPC 8 full level
C07D 487/04 (2006.01); C12N 9/20 (2006.01); C12P 17/18 (2006.01); C12P 41/00 (2006.01)
CPC (source: EP)
C07D 487/04 (2013.01); C12N 9/20 (2013.01); C12P 17/188 (2013.01); C12P 41/004 (2013.01)
Citation (search report)
See references of WO 9837081A1
Designated contracting state (EPC)
CH DE DK FR GB IT LI NL
DOCDB simple family (publication)
DE 19706336 A1 19980820; CA 2280833 A1 19980827; CN 1248258 A 20000322; EP 0966469 A1 19991229; JP 2001512468 A 20010821; WO 9837081 A1 19980827
DOCDB simple family (application)
DE 19706336 A 19970219; CA 2280833 A 19980209; CN 98802671 A 19980209; EP 9800707 W 19980209; EP 98909425 A 19980209; JP 53621198 A 19980209