EP 0966472 A1 19991229 - CEPHALOSPORIN DERIVATIVES
Title (en)
CEPHALOSPORIN DERIVATIVES
Title (de)
CEPHALOSPORIN-DERIVATE
Title (fr)
DERIVES DE CEPHALOSPORINE
Publication
Application
Priority
- US 9721785 W 19971121
- US 3404696 P 19961127
Abstract (en)
[origin: WO9823621A1] Provided are cephem derivatives represented by general formula (I) wherein Q is an optionally substituted pyridinium group connected to the sulfur atom via a ring carbon atom; X is halogen; Y is hydrogen or halogen; L<1> is a furan group, a thiophene group, a C2-C10 alkyl group, or a C2-C10 alkyl group interrupted by one or more groups independently selected from vinyl, S, SO, SO2, SO2NH, (IIa), (IIb); n is 0 or 1; A is CO2H, PO3H2, SO3H or tetrazole; and R<1> is hydrogen or a carboxyl-protecting group; and pharmaceutically acceptable salts and/or prodrugs thereof. The derivatives are gram-positive antibacterial agents especially useful in the treatment of diseases caused by methicilin-resistant Staphylococcus aureus (MRSA).
IPC 1-7
IPC 8 full level
A61K 31/546 (2006.01); A61P 31/04 (2006.01); C07D 501/00 (2006.01); C07D 501/36 (2006.01)
CPC (source: EP KR)
A61P 31/04 (2018.01 - EP); C07D 501/00 (2013.01 - EP); C07D 501/36 (2013.01 - KR); Y02P 20/55 (2015.11 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9823621 A1 19980604; AR 010650 A1 20000628; AU 5365298 A 19980622; AU 734948 B2 20010628; BR 9713350 A 20000125; CA 2272717 A1 19980604; CN 1238775 A 19991215; CZ 185399 A3 19990811; EP 0966472 A1 19991229; EP 0966472 A4 19991229; HU P9903621 A2 20000428; HU P9903621 A3 20010528; IL 129437 A0 20000217; JP 2001506607 A 20010522; KR 20000057283 A 20000915; NO 992526 D0 19990526; NO 992526 L 19990526; NZ 335892 A 20010727; PL 334558 A1 20000313; TW 414796 B 20001211; ZA 9710662 B 19990526
DOCDB simple family (application)
US 9721785 W 19971121; AR P970105544 A 19971126; AU 5365298 A 19971121; BR 9713350 A 19971121; CA 2272717 A 19971121; CN 97199930 A 19971121; CZ 185399 A 19971121; EP 97950724 A 19971121; HU P9903621 A 19971121; IL 12943797 A 19971121; JP 52485698 A 19971121; KR 19997004689 A 19990527; NO 992526 A 19990526; NZ 33589297 A 19971121; PL 33455897 A 19971121; TW 86117285 A 19971119; ZA 9710662 A 19971126