Global patent index - EP 0968205 A1

EP 0968205 A1 2000-01-05 - PROCESS FOR THE PREPARATION OF 2- (2-PYRIDINYL)METHYL SULFINYL -1H-BENZIMIDAZOLES AND NOVEL COMPOUNDS OF USE FOR SUCH PURPOSE

Title (en)

PROCESS FOR THE PREPARATION OF 2- (2-PYRIDINYL)METHYL SULFINYL -1H-BENZIMIDAZOLES AND NOVEL COMPOUNDS OF USE FOR SUCH PURPOSE

Title (de)

VERFAHREN ZUR HERSTELLUNG VON 2-¬¬(2-PYRIDINYL)METHYL SULFINYL -1H-BENZIMIDAZOLEN UND DABEI VERWENDBARE NEUE VERBINDUNGEN

Title (fr)

PROCEDE DE PREPARATION DE 2- 2-PYRIDINYL)METHYL SULFYNYL -1H-BENZIMIDAZOLES ET NOUVEAUX COMPOSES A UTILISER DANS LEDIT PROCEDE

Publication

EP 0968205 A1 (EN)

Application

EP 98902961 A

Priority

  • DK 9800059 W
  • DK 25097 A

Abstract (en)

[origin: WO9840378A1] 2-[[(2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole derivatives of general formula (V) wherein R<2> represents H, OCH3, OCHF2 or CF3, R<3> represents H, CH3 or OCH3, R<4> represents H, OCH3, OCH2CF3, halo or nitro, R<5> represents H, CH3 or OCH3, and n is 0 or 1, or salts thereof, are prepared by a new process proceeding via novel intermediates of general formulae (I), (II), (III) and (Va) wherein R<1> represents branched or straight C1-8-alkyl, C3-8-cycloalkyl, aryl, aralkyl having 1-8 C-atoms in the alkyl moiety, or a 5- or 6-membered heterocyclic group having one, two or three hetero atoms selected from nitrogen, sulfur and oxygen in the heterocyclic ring. The compounds of formula (V) are biologically active and/or may be used as intermediates in the synthesis of biologically active compounds.

IPC 1-7 (main, further and additional classification)

C07D 401/12; C07D 235/28; C07D 513/04

IPC 8 full level (invention and additional information)

C07D 235/28 (2006.01); C07D 401/12 (2006.01); C07D 513/04 (2006.01)

CPC (invention and additional information)

C07D 401/12 (2013.01); C07D 235/28 (2013.01); C07D 513/04 (2013.01)

Citation (search report)

See references of WO 9840378A1

Designated contracting state (EPC)

DE DK FI

EPO simple patent family

WO 9840378 A1 19980917; AU 5982298 A 19980929; EP 0968205 A1 20000105; HR P980115 A2 19990228; NO 994340 A 19990907; NO 994340 D0 19990907; ZA 9801732 B 19980907

INPADOC legal status

2007-11-14 [RTI1] TITLE (CORRECTION)

- Free Format Text: PROCESS FOR THE PREPARATION OF 2- (2-PYRIDINYL)METHYL SULFINYL -1H-BENZIMIDAZOLES AND NOVEL COMPOUNDS OF USE FOR SUCH PURPOSE

2002-07-17 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20020108

2001-10-10 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010827

2000-01-05 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990917

2000-01-05 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): DE DK FI