EP 0968279 A1 20000105 - METHOD FOR THE PURIFICATION AND CRYSTALLIZATION OF PROTEASOME
Title (en)
METHOD FOR THE PURIFICATION AND CRYSTALLIZATION OF PROTEASOME
Title (de)
VERFAHREN ZUR REINIGUNG UND KRISTALLISIERUNG VON PROTEASOM
Title (fr)
PROCEDE DE PURIFICATION ET DE CRISTALLISATION DE PROTEASOME
Publication
Application
Priority
- EP 98917038 A 19980320
- EP 9801653 W 19980320
- EP 97104877 A 19970321
Abstract (en)
[origin: WO9842829A1] The invention relates to a method for the production of a purified eucaryotic crystallizable proteasome preparation, and to the proteasome preparation obtained by this method. The invention also relates to a purified eucaryotic proteasome preparation in crystallized form. With the aid of crystal data from this proteasome preparation, new proteasome inhibitors can be identified and produced, in particular with the aid of computer assisted modelling programmes.
IPC 1-7
IPC 8 full level
C12N 9/60 (2006.01)
CPC (source: EP)
C12N 9/60 (2013.01); C12Y 304/25001 (2013.01)
Citation (examination)
PÜHLER G. ET AL: "Subunit stoichiometry and three-dimensional arrangement in pr oteasomes from Thermoplasma acidophilum", EMBO JOURNAL, vol. 11, no. 4, OXFORD, pages 1607 - 1616, XP001204511
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB IE IT LI NL SE
DOCDB simple family (publication)
DOCDB simple family (application)
EP 9801653 W 19980320; EP 98917038 A 19980320