EP 0968301 A2 20000105 - TRANSGLYCOLYTIC SYNTHESIS OF BRANCHED OLIGOSACCHARIDES
Title (en)
TRANSGLYCOLYTIC SYNTHESIS OF BRANCHED OLIGOSACCHARIDES
Title (de)
TRANSGLYKOLYTISCHE SYNTHESE VERZWEIGTER OLIGOSACCHARIDE
Title (fr)
SYNTHESE TRANSGLYCOLYTIQUE D'OLIGOSACCHARIDES RAMIFIES
Publication
Application
Priority
- EP 9801393 W 19980311
- IT MI970566 A 19970313
Abstract (en)
[origin: WO9840512A2] The invention relates to a process exclusively relying on transglycolytic enzymes, for the synthesis of branched oligosaccharides. According to the described process, a donor saccharide is first incubated with an acceptor saccharide and with a suitable glycosidase. The resulting di- or oligosaccharide is then incubated with a second, different glycosidase and with a donor saccharide, to form a second glucosidic bond differing from the one formed in the first stage, thereby obtaining a branched oligosaccharide. The process is entirely and exclusively performed in water phase and allows to obtain, with high yield and specificity, branched oligosaccharides such as the trisaccharide Lewis-X.
IPC 1-7
IPC 8 full level
C07H 3/06 (2006.01); C12P 19/14 (2006.01)
CPC (source: EP)
C07H 3/06 (2013.01); C12P 19/14 (2013.01)
Citation (search report)
See references of WO 9840512A2
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB IE IT LI NL PT SE
DOCDB simple family (publication)
WO 9840512 A2 19980917; WO 9840512 A3 19981210; AU 6830198 A 19980929; EP 0968301 A2 20000105; IT 1290071 B1 19981019; IT MI970566 A1 19980913
DOCDB simple family (application)
EP 9801393 W 19980311; AU 6830198 A 19980311; EP 98913699 A 19980311; IT MI970566 A 19970313