Global patent index - EP 0968301 A2

EP 0968301 A2 2000-01-05 - TRANSGLYCOLYTIC SYNTHESIS OF BRANCHED OLIGOSACCHARIDES

Title (en)

TRANSGLYCOLYTIC SYNTHESIS OF BRANCHED OLIGOSACCHARIDES

Title (de)

TRANSGLYKOLYTISCHE SYNTHESE VERZWEIGTER OLIGOSACCHARIDE

Title (fr)

SYNTHESE TRANSGLYCOLYTIQUE D'OLIGOSACCHARIDES RAMIFIES

Publication

EP 0968301 A2 (EN)

Application

EP 98913699 A

Priority

  • EP 9801393 W
  • IT MI970566 A

Abstract (en)

[origin: WO9840512A2] The invention relates to a process exclusively relying on transglycolytic enzymes, for the synthesis of branched oligosaccharides. According to the described process, a donor saccharide is first incubated with an acceptor saccharide and with a suitable glycosidase. The resulting di- or oligosaccharide is then incubated with a second, different glycosidase and with a donor saccharide, to form a second glucosidic bond differing from the one formed in the first stage, thereby obtaining a branched oligosaccharide. The process is entirely and exclusively performed in water phase and allows to obtain, with high yield and specificity, branched oligosaccharides such as the trisaccharide Lewis-X.

IPC 1-7 (main, further and additional classification)

C12P 19/14; C07H 3/06; C12N 9/24; C12N 9/38

IPC 8 full level (invention and additional information)

C07H 3/06 (2006.01); C12P 19/14 (2006.01)

CPC (invention and additional information)

C07H 3/06 (2013.01); C12P 19/14 (2013.01)

Citation (search report)

See references of WO 9840512A2

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB IE IT LI NL PT SE

EPO simple patent family

WO 9840512 A2 19980917; WO 9840512 A3 19981210; AU 6830198 A 19980929; EP 0968301 A2 20000105; IT 1290071 B1 19981019; IT MI970566 A1 19980914

INPADOC legal status

2002-05-15 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20011002

2000-02-09 [RAP3] CORRECTION OF THE ADDRESS OR NAME OF APPLICANT (A DOCUMENT)

- Owner name: SOCIETA' COOPERATIVA CENTRO RICERCHE POLY-TECH A R

2000-01-05 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990928

2000-01-05 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH DE DK ES FI FR GB IE IT LI NL PT SE

2000-01-05 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free Format Text: SI PAYMENT 19990928