Global patent index - EP 0969831 A1

EP 0969831 A1 2000-01-12 - NASAL MELATONIN COMPOSITION

Title (en)

NASAL MELATONIN COMPOSITION

Title (de)

MELATONINHALTIGE NASENARZNEIMITTEL

Title (fr)

COMPOSITION PERMETTANT L'ADMINISTRATION NASALE DE MELATONINE

Publication

EP 0969831 A1 (EN)

Application

EP 98920488 A

Priority

  • EP 98920488 A
  • EP 9801783 W
  • EP 97200920 A

Abstract (en)

[origin: EP0867181A1] The invention relates to a pharmaceutical composition for nasal administration comprising melatonin and an additive selected from glycerol, cyclodextrin, and mixtures thereof. The pharmaceutical composition comprising an aqueous composition of 0.5 to 10 mg/ml of melatonin, and one or more of 1 to 250 mg/ml of cyclodextrin and 5 to 50% by volume of glycerol, can be used for the preparation of a nasal dosage form comprising daily dosage units of 0.05 to 1 mg of melatonin, and preferably of about 0.1 to 0.8 mg of melatonin, for sleep induction in men.

IPC 1-7 (main, further and additional classification)

A61K 31/40; A61K 9/00; A61K 47/48

IPC 8 full level (invention and additional information)

A61K 9/00 (2006.01); A61K 31/40 (2006.01); A61K 31/4045 (2006.01); A61K 47/48 (2006.01)

CPC (invention and additional information)

B82Y 5/00 (2013.01); A61K 9/0043 (2013.01); A61K 31/4045 (2013.01); A61K 47/48961 (2013.01); A61K 47/48969 (2013.01)

Citation (search report)

See references of WO 9842333A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

EP 0867181 A1 19980930; EP 0969831 A1 20000112; WO 9842333 A1 19981001

INPADOC legal status

2004-02-25 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030823

2002-03-06 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020121

2000-01-12 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990907

2000-01-12 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE