Global Patent Index - EP 0969874 A1

EP 0969874 A1 20000112 - PHARMACEUTICAL COMPOSITIONS CONTAINING PROPANAMINE DERIVATIVES AND CYCLODEXTRIN

Title (en)

PHARMACEUTICAL COMPOSITIONS CONTAINING PROPANAMINE DERIVATIVES AND CYCLODEXTRIN

Title (de)

PHARMAZEUTISCHE ZUSAMMENSETZUNGEN ENTHALTENDE DERIVATE VON ZYKLODEXTRIN UND PROPANAMINE

Title (fr)

COMPOSITIONS PHARMACEUTIQUES CONTENANT DES DERIVES DE PROPANAMINE ET DE LA CYCLODEXTRINE

Publication

EP 0969874 A1 (EN)

Application

EP 98913968 A

Priority

  • HU 9800028 W
  • HU 9700632 A

Abstract (en)

[origin: WO9842382A1] A pharmaceutical composition, process for its preparation and method of antidepressive treatment with said composition containing a propanamine of general formula (I) - where R stands for hydrogen or methyl - or any optical isomer and/or pharmaceutically acceptable salt thereof together with a cyclodextrin preferably in the form of an inclusion complex. Said composition may optionally further contain auxiliary and additional materials acceptable in pharmaceuticals for oral, parenteral, transdermal, rectal or other medical use. Cyclodextrins of preference are gamma -cyclodextrin, a methylated alpha -, beta - or gamma -cyclodextrin, a hydroxypropylated alpha -, beta - or gamma -cyclodextrin, an ionic watersoluble alpha -, beta -, or gamma -cyclodextrin polymer, a maltosylated alpha -, beta - or gamma -cyclodextrin. The invention also covers the inclusion complexes and their preparation. The most preferred inclusion complex is the one containing (+/-), (-) or (+) gamma -[4-(trifluoromethyl)-phenoxy]benzene-propanamine and gamma -cyclodextrin.

IPC 1-7

A61K 47/48

IPC 8 full level

A61K 31/137 (2006.01); A61K 47/48 (2006.01); A61P 25/24 (2006.01)

CPC (source: EP)

A61K 47/6951 (2017.08); A61P 25/24 (2018.01); B82Y 5/00 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9842382 A1 19981001; AR 010910 A1 20000712; AU 6848198 A 19981020; EP 0969874 A1 20000112; HR P980155 A2 19981231; HU 9700632 A2 19981228; HU 9700632 A3 19991028; HU 9700632 D0 19970528; JP 2002514210 A 20020514; ZA 9802457 B 19980923

DOCDB simple family (application)

HU 9800028 W 19980323; AR P980101328 A 19980324; AU 6848198 A 19980323; EP 98913968 A 19980323; HR P980155 A 19980323; HU 9700632 A 19970324; JP 54325498 A 19980323; ZA 9802457 A 19980323