EP 0970053 A1 20000112 - 5-OXYSUBSTITUTED CHINOLINES AND THEIR USE AS CHOLESTEROL ESTER TRANSFER PROTEINS INHIBITORS
Title (en)
5-OXYSUBSTITUTED CHINOLINES AND THEIR USE AS CHOLESTEROL ESTER TRANSFER PROTEINS INHIBITORS
Title (de)
5-OXYSUBSTITUIERTE CHINOLINE UND IHRE VERWENDUNG ALS INHIBITOREN DES CHOLESTERIN-ESTER-TRANSFER-PROTEINS (CTEP)
Title (fr)
QUINOLINES A SUBSTITUTION OXY EN POSITION 5 ET LEUR UTILISATION COMME INHIBITEURS DE LA PROTEINE DE TRANSFERT D'ESTER DE CHOLESTEROL
Publication
Application
Priority
- DE 19709125 A 19970306
- EP 9801046 W 19980224
Abstract (en)
[origin: DE19709125A1] The invention relates to substituted chinolines of general formula (I) which are highly effective inhibitors of cholesterol ester transfer proteins (CTEP) and stimulate reverse cholesterol transfer. The inventive substances lower the LDL cholesterol level in the blood while at the same time increasing the HDL cholesterol level. Said substances can therefore be used in the treatment and prevention of hyperlipoproteinemia, hypolipoproteinimia, dyslipidiemia, hypertriglyceridemia, combined hyperlipidemia or arteriosclerosis.
IPC 1-7
IPC 8 full level
A61K 31/47 (2006.01); A61P 3/06 (2006.01); A61P 9/10 (2006.01); A61P 43/00 (2006.01); C07D 215/20 (2006.01); C07D 215/48 (2006.01); C07F 7/18 (2006.01)
CPC (source: EP)
A61P 3/06 (2017.12); A61P 9/10 (2017.12); A61P 43/00 (2017.12); C07D 215/20 (2013.01); C07F 7/1804 (2013.01)
Citation (search report)
See references of WO 9839299A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
DE 19709125 A1 19980910; AU 6724598 A 19980922; EP 0970053 A1 20000112; JP 2001513790 A 20010904; WO 9839299 A1 19980911
DOCDB simple family (application)
DE 19709125 A 19970306; AU 6724598 A 19980224; EP 9801046 W 19980224; EP 98912383 A 19980224; JP 53811498 A 19980224