EP 0970054 A1 20000112 - 1-(ISOQUINOLIN-1-YL)-4-(1-PHENYLMETHYL)PIPERAZINES; DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS
Title (en)
1-(ISOQUINOLIN-1-YL)-4-(1-PHENYLMETHYL)PIPERAZINES; DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS
Title (de)
1-(ISOCHINOLIN-1-YL)-4-(1-PHENYLMETHYL)-PIPERAZINE; DOPAMIN-REZEPTOR-SUBTYP-SPEZIFISCHE LIGANDEN
Title (fr)
1-(ISOQUINOLINE-1YL)-4-(PHENYLMETHYLE)PIPERAZINES, LIGANDS SPECIFIQUES DU SOUS-TYPE DU RECEPTEUR DE LA DOPAMINE
Publication
Application
Priority
- US 9804051 W 19980303
- US 81072997 A 19970304
Abstract (en)
[origin: WO9839301A1] Disclosed are compounds useful in treating psychotic disorders such as schizophrenia and other central nervous system diseases, where the compounds have general Formula (I), wherein: Ar represents an aryl or heteroaryl group; R1 and R2 independently represent hydrogen, halogen, C1-C6 alkyl, C1-C4 alkoxy, C1-C4 alkylthio, hydroxy, amino, mono- or di(C1-C6)alkyl amino, cyano or trifluoromethyl; and R5 represents hydrogen or C1-C6 alkyl.
IPC 1-7
IPC 8 full level
A61K 31/496 (2006.01); A61P 25/18 (2006.01); C07D 217/22 (2006.01); C07D 405/12 (2006.01)
CPC (source: EP KR)
A61P 25/18 (2018.01 - EP); C07D 217/22 (2013.01 - EP KR); C07D 405/12 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9839301 A1 19980911; AU 6678598 A 19980922; CA 2283256 A1 19980911; EP 0970054 A1 20000112; HU P0001391 A2 20001028; HU P0001391 A3 20011228; IL 131427 A0 20010128; JP 2001512491 A 20010821; KR 20000075918 A 20001226; NZ 337183 A 20010525
DOCDB simple family (application)
US 9804051 W 19980303; AU 6678598 A 19980303; CA 2283256 A 19980303; EP 98908854 A 19980303; HU P0001391 A 19980303; IL 13142798 A 19980303; JP 53866498 A 19980303; KR 19997007998 A 19990903; NZ 33718398 A 19980303