Global Patent Index - EP 0970054 A1

EP 0970054 A1 20000112 - 1-(ISOQUINOLIN-1-YL)-4-(1-PHENYLMETHYL)PIPERAZINES; DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS

Title (en)

1-(ISOQUINOLIN-1-YL)-4-(1-PHENYLMETHYL)PIPERAZINES; DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS

Title (de)

1-(ISOCHINOLIN-1-YL)-4-(1-PHENYLMETHYL)-PIPERAZINE; DOPAMIN-REZEPTOR-SUBTYP-SPEZIFISCHE LIGANDEN

Title (fr)

1-(ISOQUINOLINE-1YL)-4-(PHENYLMETHYLE)PIPERAZINES, LIGANDS SPECIFIQUES DU SOUS-TYPE DU RECEPTEUR DE LA DOPAMINE

Publication

EP 0970054 A1 20000112 (EN)

Application

EP 98908854 A 19980303

Priority

  • US 9804051 W 19980303
  • US 81072997 A 19970304

Abstract (en)

[origin: WO9839301A1] Disclosed are compounds useful in treating psychotic disorders such as schizophrenia and other central nervous system diseases, where the compounds have general Formula (I), wherein: Ar represents an aryl or heteroaryl group; R1 and R2 independently represent hydrogen, halogen, C1-C6 alkyl, C1-C4 alkoxy, C1-C4 alkylthio, hydroxy, amino, mono- or di(C1-C6)alkyl amino, cyano or trifluoromethyl; and R5 represents hydrogen or C1-C6 alkyl.

IPC 1-7

C07D 217/22

IPC 8 full level

A61K 31/496 (2006.01); A61P 25/18 (2006.01); C07D 217/22 (2006.01); C07D 405/12 (2006.01)

CPC (source: EP)

A61P 25/18 (2018.01); C07D 217/22 (2013.01); C07D 405/12 (2013.01)

Citation (search report)

See references of WO 9839301A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9839301 A1 19980911; AU 6678598 A 19980922; CA 2283256 A1 19980911; EP 0970054 A1 20000112; HU 0001391 A2 20001028; HU 0001391 A3 20011228; IL 131427 D0 20010128; JP 2001512491 A 20010821; KR 20000075918 A 20001226; NZ 337183 A 20010525

DOCDB simple family (application)

US 9804051 W 19980303; AU 6678598 A 19980303; CA 2283256 A 19980303; EP 98908854 A 19980303; HU 0001391 A 19980303; IL 13142798 A 19980303; JP 53866498 A 19980303; KR 19997007998 A 19990903; NZ 33718398 A 19980303