Global Patent Index - EP 0970054 A1

EP 0970054 A1 2000-01-12 - 1-(ISOQUINOLIN-1-YL)-4-(1-PHENYLMETHYL)PIPERAZINES; DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS

Title (en)

1-(ISOQUINOLIN-1-YL)-4-(1-PHENYLMETHYL)PIPERAZINES; DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS

Title (de)

1-(ISOCHINOLIN-1-YL)-4-(1-PHENYLMETHYL)-PIPERAZINE; DOPAMIN-REZEPTOR-SUBTYP-SPEZIFISCHE LIGANDEN

Title (fr)

1-(ISOQUINOLINE-1YL)-4-(PHENYLMETHYLE)PIPERAZINES, LIGANDS SPECIFIQUES DU SOUS-TYPE DU RECEPTEUR DE LA DOPAMINE

Publication

EP 0970054 A1 (EN)

Application

EP 98908854 A

Priority

  • US 9804051 W
  • US 81072997 A

Abstract (en)

[origin: WO9839301A1] Disclosed are compounds useful in treating psychotic disorders such as schizophrenia and other central nervous system diseases, where the compounds have general Formula (I), wherein: Ar represents an aryl or heteroaryl group; R1 and R2 independently represent hydrogen, halogen, C1-C6 alkyl, C1-C4 alkoxy, C1-C4 alkylthio, hydroxy, amino, mono- or di(C1-C6)alkyl amino, cyano or trifluoromethyl; and R5 represents hydrogen or C1-C6 alkyl.

IPC 1-7 (main, further and additional classification)

C07D 217/22

IPC 8 full level (invention and additional information)

A61K 31/496 (2006.01); A61P 25/18 (2006.01); C07D 217/22 (2006.01); C07D 405/12 (2006.01)

CPC (invention and additional information)

C07D 405/12 (2013.01); C07D 217/22 (2013.01)

Citation (search report)

See references of WO 9839301A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9839301 A1 19980911; AU 6678598 A 19980922; CA 2283256 A1 19980911; EP 0970054 A1 20000112; HU 0001391 A2 20001028; HU 0001391 A3 20011228; IL 131427 D0 20010128; JP 2001512491 A 20010821; KR 20000075918 A 20001226; NZ 337183 A 20010525

INPADOC legal status


2003-09-17 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20030308

2002-10-16 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20020828

2000-01-12 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19990923

2000-01-12 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-01-12 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: AL PAYMENT 19990923;LT PAYMENT 19990923;LV PAYMENT 19990923;MK PAYMENT 19990923;RO PAYMENT 19990923;SI PAYMENT 19990923