Global Patent Index - EP 0970115 A1

EP 0970115 A1 20000112 - VIRAL PEPTIDES WITH STRUCTURAL HOMOLOGY TO PROTEIN G OF RESPIRATORY SYNCYTIAL VIRUS

Title (en)

VIRAL PEPTIDES WITH STRUCTURAL HOMOLOGY TO PROTEIN G OF RESPIRATORY SYNCYTIAL VIRUS

Title (de)

VIRALE PEPTIDE MIT STRUKTURELLER HOMOLOGIE ZU PROTEIN G AUS RESPIRATORY SYNCYTIAL VIRUS (RSV)

Title (fr)

PEPTIDES VIRAUX PRESENTANT UNE HOMOLOGIE STRUCTURELLE AVEC LA PROTEINE G DU VIRUS RESPIRATOIRE SYNCYTIAL BOVIN

Publication

EP 0970115 A1 20000112 (EN)

Application

EP 97923671 A 19970604

Priority

  • AU 9700351 W 19970604
  • AU PO026596 A 19960605

Abstract (en)

[origin: WO9746581A1] This invention relates to compounds having structural homology to a contiguous sequence of amino acids within the sequence representing residues 149-197 of the G protein of respiratory syncytial virus, in which a) no oligosaccharide is linked to potential serine, threonine or asparagine attachment sites; b) four cysteine residues are involved in disulphide linkages; and c) the pattern of disulphide linkage is Cys 173 linked to Cys 186, and Cys 176 linked to Cys 182, and in which said compounds possess a biological activity of respiratory syncytial virus G protein, and also encompass biologically-active peptidomimetic and other analogues of these compounds, and antibodies thereto. The compounds of the invention are useful as therapeutic, diagnostic, and screening agents in relation to Pneumoviruses, especially respiratory syncytial virus.

IPC 1-7

C07K 14/135; A61K 39/155; G01N 33/68; G01N 33/569

IPC 8 full level

A61K 31/00 (2006.01); A61K 38/00 (2006.01); A61K 39/155 (2006.01); A61K 39/395 (2006.01); A61P 31/00 (2006.01); A61P 31/14 (2006.01); C07K 14/135 (2006.01); C07K 16/08 (2006.01); C12N 5/10 (2006.01); C12N 15/02 (2006.01); C12N 15/09 (2006.01); C12P 21/08 (2006.01); G01N 33/569 (2006.01)

CPC (source: EP)

A61P 31/00 (2017.12); A61P 31/14 (2017.12); C07K 14/005 (2013.01); A61K 38/00 (2013.01); C12N 2760/18522 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9746581 A1 19971211; AU PO026596 A0 19960627; CA 2257943 A1 19971211; CN 1227565 A 19990901; EP 0970115 A1 20000112; EP 0970115 A4 20020213; JP 2000512136 A 20000919; NZ 333107 A 20000825

DOCDB simple family (application)

AU 9700351 W 19970604; AU PO026596 A 19960605; CA 2257943 A 19970604; CN 97197103 A 19970604; EP 97923671 A 19970604; JP 50001698 A 19970604; NZ 33310797 A 19970604