Global patent index - EP 0970233 A1

EP 0970233 A1 2000-01-12 - METHODS AND COMPOSITIONS FOR GENETICALLY MODIFYING PRIMATE BONE MARROW CELLS

Title (en)

METHODS AND COMPOSITIONS FOR GENETICALLY MODIFYING PRIMATE BONE MARROW CELLS

Title (de)

VERFAHREN UND ZUSAMMENSETZUNGEN ZUR GENETISCHEN VERÄNDERUNG VON PRIMATEN KNOCHENMARKZELLEN

Title (fr)

PROCEDES ET COMPOSITIONS DESTINES A MODIFIER GENETIQUEMENT DES CELLULES MEDULLAIRES DE PRIMATE

Publication

EP 0970233 A1 (EN)

Application

EP 98909876 A

Priority

  • NL 9800154 W
  • US 82047997 A

Abstract (en)

[origin: WO9841644A1] A method is provided for genetically modifying primate bone marrow cells, comprising isolating bone marrow cells from a primate and, by means of cocultivation, exposing the isolated bone marrow cells to cells that produce a recombinant amphotropic retrovirus with a genome based on a retroviral vector that contains the genetic information to be introduced into the bone marrow cells. Recombinant amphotropic retrovirus-producing cells, suitable for use in this method also are provided, as genetically modified primate bone marrow cells with the capacity for regeneration in vivo.

IPC 1-7 (main, further and additional classification)

C12N 15/86; C12N 5/06; C12N 15/64; C12N 15/87

IPC 8 full level (invention and additional information)

C12N 15/867 (2006.01)

CPC (invention and additional information)

C12N 15/86 (2013.01); C12N 2740/13043 (2013.01); C12N 2740/13045 (2013.01); C12N 2810/6054 (2013.01); C12N 2810/855 (2013.01)

Citation (search report)

See references of WO 9841644A1

Designated contracting state (EPC)

BE CH DE ES FR GB IT LI LU NL

EPO simple patent family

WO 9841644 A1 19980924; AU 6424498 A 19981012; CA 2283641 A1 19980924; EP 0970233 A1 20000112; NZ 337945 A 20011026

INPADOC legal status

2004-11-03 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20040414

2004-01-14 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20031202

2003-04-02 [RAP1] TRANSFER OF RIGHTS OF AN EP APPLICATION

- Owner name: CRUCELL HOLLAND B.V.

2000-01-12 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990923

2000-01-12 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): BE CH DE ES FR GB IT LI LU NL