EP 0970233 A1 20000112 - METHODS AND COMPOSITIONS FOR GENETICALLY MODIFYING PRIMATE BONE MARROW CELLS
Title (en)
METHODS AND COMPOSITIONS FOR GENETICALLY MODIFYING PRIMATE BONE MARROW CELLS
Title (de)
VERFAHREN UND ZUSAMMENSETZUNGEN ZUR GENETISCHEN VERÄNDERUNG VON PRIMATEN KNOCHENMARKZELLEN
Title (fr)
PROCEDES ET COMPOSITIONS DESTINES A MODIFIER GENETIQUEMENT DES CELLULES MEDULLAIRES DE PRIMATE
Publication
Application
Priority
- NL 9800154 W 19980317
- US 82047997 A 19970318
Abstract (en)
[origin: WO9841644A1] A method is provided for genetically modifying primate bone marrow cells, comprising isolating bone marrow cells from a primate and, by means of cocultivation, exposing the isolated bone marrow cells to cells that produce a recombinant amphotropic retrovirus with a genome based on a retroviral vector that contains the genetic information to be introduced into the bone marrow cells. Recombinant amphotropic retrovirus-producing cells, suitable for use in this method also are provided, as genetically modified primate bone marrow cells with the capacity for regeneration in vivo.
IPC 1-7
IPC 8 full level
C12N 15/867 (2006.01)
CPC (source: EP)
C12N 15/86 (2013.01); C12N 2740/13043 (2013.01); C12N 2740/13045 (2013.01); C12N 2810/6054 (2013.01); C12N 2810/855 (2013.01)
Citation (search report)
See references of WO 9841644A1
Designated contracting state (EPC)
BE CH DE ES FR GB IT LI LU NL
DOCDB simple family (publication)
WO 9841644 A1 19980924; AU 6424498 A 19981012; CA 2283641 A1 19980924; EP 0970233 A1 20000112; NZ 337945 A 20011026
DOCDB simple family (application)
NL 9800154 W 19980317; AU 6424498 A 19980317; CA 2283641 A 19980317; EP 98909876 A 19980317; NZ 33794598 A 19980317