EP 0970241 A1 20000112 - (IN VITRO) EVOLUTION OF OLIGONUCLEOTIDES
Title (en)
(IN VITRO) EVOLUTION OF OLIGONUCLEOTIDES
Title (de)
IN VITRO EVOLUTION VON OLIGONUKLEOTIDEN
Title (fr)
EVOLUTION IN VITRO D'OLIGONUCLEOTIDES
Publication
Application
Priority
- IL 9700283 W 19970826
- IL 12046697 A 19970317
Abstract (en)
[origin: WO9841654A1] The present invention concerns a method for in vitro evolution of oligonucleotides. In the method of the invention the negative selection step, in which undesired oligonucleotides are removed, utilizes a unique random tag sequence attached to the evolving oligonucleotides which enables to eliminate, by hybridization, undesired oligonucleotides.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); C12N 15/10 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2006.01)
CPC (source: EP)
C12N 15/1048 (2013.01); C12N 15/1058 (2013.01); C12N 15/1072 (2013.01); C12N 15/113 (2013.01); C07K 2319/00 (2013.01); C12N 2310/124 (2013.01); C12Q 1/6811 (2013.01)
Citation (search report)
See references of WO 9841654A1
Designated contracting state (EPC)
CH DE ES FR GB IT LI
DOCDB simple family (publication)
WO 9841654 A1 19980924; AU 3862197 A 19981012; EP 0970241 A1 20000112; IL 120466 A0 19970713; JP 2001515358 A 20010918
DOCDB simple family (application)
IL 9700283 W 19970826; AU 3862197 A 19970826; EP 97935737 A 19970826; IL 12046697 A 19970317; JP 54028898 A 19970826