Global Patent Index - EP 0970241 A1

EP 0970241 A1 2000-01-12 - (IN VITRO) EVOLUTION OF OLIGONUCLEOTIDES

Title (en)

(IN VITRO) EVOLUTION OF OLIGONUCLEOTIDES

Title (de)

IN VITRO EVOLUTION VON OLIGONUKLEOTIDEN

Title (fr)

EVOLUTION IN VITRO D'OLIGONUCLEOTIDES

Publication

EP 0970241 A1 (EN)

Application

EP 97935737 A

Priority

  • IL 9700283 W
  • IL 12046697 A

Abstract (en)

[origin: WO9841654A1] The present invention concerns a method for in vitro evolution of oligonucleotides. In the method of the invention the negative selection step, in which undesired oligonucleotides are removed, utilizes a unique random tag sequence attached to the evolving oligonucleotides which enables to eliminate, by hybridization, undesired oligonucleotides.

IPC 1-7

C12Q 1/68

IPC 8 full level

C12N 15/09 (2006.01); C12N 15/10 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2006.01)

CPC

C12N 15/1058 (2013.01); C12N 15/1048 (2013.01); C12N 15/1072 (2013.01); C12N 15/113 (2013.01); C07K 2319/00 (2013.01); C12N 2310/124 (2013.01); C12Q 1/6811 (2013.01)

Citation (search report)

See references of WO 9841654A1

DCS

CH DE ES FR GB IT LI

DOCDB simple family

WO 9841654 A1 19980924; AU 3862197 A 19981012; EP 0970241 A1 20000112; IL 120466 D0 19970713; JP 2001515358 A 20010918