Global Patent Index - EP 0970374 A1

EP 0970374 A1 20000112 - BIOSENSOR FOR CELLS

Title (en)

BIOSENSOR FOR CELLS

Title (de)

BIOSENSOR FÜR ZELLEN

Title (fr)

BIOCAPTEUR POUR CELLULES

Publication

EP 0970374 A1 20000112 (EN)

Application

EP 98908267 A 19980313

Priority

  • IL 9800119 W 19980313
  • IL 12044597 A 19970313

Abstract (en)

[origin: WO9840739A1] A system and method for assaying presence and optionally concentration of cells in a liquid medium, as well as a sensing member for use in the system or method, are provided. The sensing member comprises a piezoelectric crystal provided on its surface with a metal plate in which there are immobilized specific binding entities which specifically bind to an epitope on the surface of said cells. Binding or release of the cells from the specific binding entities causes a change in mass and hence a change in resonance frequency of the piezoelectric crystal. Measuring the change in the resonance frequency provides an indication of presence of the assayed cells in a medium. Determining of the extent of change in resonance frequency may be used to determine the concentration of the cells in the medium. By a specific embodiment the assayed cells are chlamydia and the liquid medium is urine.

IPC 1-7

G01N 33/543; G01N 27/327

IPC 8 full level

G01N 33/543 (2006.01)

CPC (source: EP)

G01N 33/54373 (2013.01)

Citation (search report)

See references of WO 9840739A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9840739 A1 19980917; AU 6634298 A 19980929; EP 0970374 A1 20000112; IL 120445 A0 19970713

DOCDB simple family (application)

IL 9800119 W 19980313; AU 6634298 A 19980313; EP 98908267 A 19980313; IL 12044597 A 19970313