Global patent index - EP 0971712 A1

EP 0971712 A1 2000-01-19 - COMPOSITIONS FOR THE INHIBITION OF BONE RESORPTION

Title (en)

COMPOSITIONS FOR THE INHIBITION OF BONE RESORPTION

Title (de)

ZUSAMMENSTELLUNG ZUR VERHINDERUNG VON KNOCHENABBAU

Title (fr)

COMPOSITIONS PERMETTANT D'INHIBER LA RESORPTION OSSEUSE

Publication

EP 0971712 A1 (EN)

Application

EP 98903203 A

Priority

  • GB 9800443 W
  • GB 9703109 A

Abstract (en)

[origin: WO9835674A1] The disclosed invention is based on the observation that functional NMDA receptors are present on osteoclasts. Use of NMDA antagonists to inhibit bone resorption is disclosed, useful therefore in the treatment of bone disorders such as osteoporosis and Paget's disease. The NMDA antagonists used were Phencyclidine and Dizocilpine.

IPC 1-7 (main, further and additional classification)

A61K 31/445; A61K 31/46

IPC 8 full level (invention and additional information)

C07D 215/22 (2006.01); A61K 31/191 (2006.01); A61K 31/194 (2006.01); A61K 31/404 (2006.01); A61K 31/445 (2006.01); A61K 31/451 (2006.01); A61K 31/46 (2006.01); A61K 31/4704 (2006.01); A61K 31/498 (2006.01); A61K 31/4985 (2006.01); A61K 31/5025 (2006.01); A61K 31/529 (2006.01); A61K 31/662 (2006.01); A61K 31/7105 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 3/14 (2006.01); A61P 19/08 (2006.01); A61P 19/10 (2006.01); C07D 211/14 (2006.01); C07D 241/42 (2006.01); C07D 241/44 (2006.01); C07D 471/04 (2006.01); C07D 471/08 (2006.01); C07D 487/04 (2006.01); C07D 487/06 (2006.01)

CPC (invention and additional information)

A61K 31/46 (2013.01); A61K 31/451 (2013.01)

Citation (search report)

See references of WO 9835674A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9835674 A1 19980820; AU 6001798 A 19980908; CA 2280722 A1 19980820; EP 0971712 A1 20000119; GB 9703109 D0 19970402; JP 2001513757 A 20010904; ZA 9801206 B 19990326

INPADOC legal status

2002-03-13 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20010406

2001-06-13 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20010426

2000-06-28 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: SMITH & NEPHEW PLC

- Ref Legal Event Code: RAP1

2000-01-19 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19990910

2000-01-19 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE