Global Patent Index - EP 0971744 A2

EP 0971744 A2 2000-01-19 - COMBINATION THERAPY EMPLOYING ILEAL BILE ACID TRANSPORT INHIBITING BENZOTHIEPINES AND HMG Co-A REDUCTASE INHIBITORS

Title (en)

COMBINATION THERAPY EMPLOYING ILEAL BILE ACID TRANSPORT INHIBITING BENZOTHIEPINES AND HMG Co-A REDUCTASE INHIBITORS

Title (de)

ZUSAMMENSETZUNGEN WELCHE BENZOTHIEPINEN MIT WIRKUNG ALS INHIBITOREN DES GALLENSÄURETRANSPORTS UND HMG-COA REDUKTASE-HEMMERN ENTHALTEN

Title (fr)

TRAITEMENT ASSOCIE UTILISANT DES BENZOTHIEPINES INHIBITRICES DU TRANSPORT ILEAL DE L'ACIDE BILIAIRE ET DES INHIBITEURS DE LA HMG Co-A REDUCTASE

Publication

EP 0971744 A2 (EN)

Application

EP 98910075 A

Priority

  • US 9803792 W
  • US 4066097 P

Abstract (en)

[origin: WO9840375A2] Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals. Also provided are compositions and methods for combination therapy employing ileal bile acid transport inhibitors and HMG Co-A reductase inhibitors for the treatment of hyperlipidemic conditions.

IPC 1-7 (main, further and additional classification)

A61K 45/06

IPC 8 full level (invention and additional information)

C07D 337/08 (2006.01); A61K 31/19 (2006.01); A61K 31/22 (2006.01); A61K 31/366 (2006.01); A61K 31/38 (2006.01); A61K 31/381 (2006.01); A61K 31/395 (2006.01); A61K 31/4025 (2006.01); A61K 31/4035 (2006.01); A61K 31/405 (2006.01); A61K 31/4178 (2006.01); A61K 31/437 (2006.01); A61K 31/4375 (2006.01); A61K 31/4436 (2006.01); A61K 31/4709 (2006.01); A61K 31/4725 (2006.01); A61K 31/473 (2006.01); A61K 31/496 (2006.01); A61K 31/498 (2006.01); A61K 31/4995 (2006.01); A61K 31/502 (2006.01); A61K 31/5377 (2006.01); A61K 31/55 (2006.01); A61K 31/67 (2006.01); A61K 45/06 (2006.01); A61P 3/06 (2006.01); C07D 409/04 (2006.01); C07D 409/10 (2006.01); C07D 409/12 (2006.01); C07D 409/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 487/08 (2006.01)

CPC (invention and additional information)

A61K 45/06 (2013.01); A61K 31/22 (2013.01); A61K 31/366 (2013.01); A61K 31/405 (2013.01)

Combination set (CPC)

  1. A61K 31/22 + A61K 2300/00
  2. A61K 31/366 + A61K 2300/00
  3. A61K 31/405 + A61K 2300/00

Citation (search report)

See references of WO 9840375A3

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9840375 A2 19980917; WO 9840375 A3 19981203; AU 6440898 A 19980929; AU 730024 B2 20010222; AU 730024 C 20040805; BG 103793 A 20000731; BR 9808013 A 20010925; CA 2283575 A1 19980917; CN 1255864 A 20000607; EP 0971744 A2 20000119; HU 0002395 A2 20010528; HU 0002395 A3 20021228; IL 131872 D0 20010319; JP 2002500628 A 20020108; MX PA99008417 A 20050203; NO 994390 A 19991104; NO 994390 D0 19990910; NZ 337830 A 20010727; PL 336415 A1 20000619; RU 2247579 C2 20050310; SK 125099 A3 20010212

INPADOC legal status


2007-04-25 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20061003

2005-04-20 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: G.D. SEARLE LLC.

2000-01-19 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990924

2000-01-19 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE