Global patent index - EP 0971952 A2

EP 0971952 A2 2000-01-19 - DIAGNOSIS METHOD AND REAGENTS

Title (en)

DIAGNOSIS METHOD AND REAGENTS

Title (de)

DIAGNOSEVERFAHREN UND REAGENZIEN

Title (fr)

REACTIFS POUR DIAGNOSTICS ET PROCEDE CORRESPONDANT

Publication

EP 0971952 A2 (EN)

Application

EP 98917502 A

Priority

  • IB 9800705 W
  • US 4316397 P

Abstract (en)

[origin: WO9845322A2] The invention relates to methods and reagents for the diagnosis and treatment of a disease caused by or associated with an RNA molecule having a transcript mutation giving rise to a frameshift mutation. The diagnostic methods include the steps of providing a body fluid or tissue sample from a patient; and analyzing the sample for the presence of an RNA molecule having a frameshift mutation or a protein encoded thereby, wherein the presence of the mutated RNA molecule or encoded protein is indicative of the disease. The therapeutic treatments include administering substances which selectively eliminate mutate RNA molecule from the cell.

IPC 1-7 (main, further and additional classification)

C07K 14/00; A61K 48/00; C12N 15/85; C12Q 1/68; G01N 33/53

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 9/127 (2006.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01); A61K 35/28 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 3/10 (2006.01); A61P 21/04 (2006.01); A61P 25/14 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/47 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12Q 1/68 (2006.01); G01N 33/68 (2006.01)

CPC (invention and additional information)

G01N 33/6896 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6858 (2013.01); C12Q 1/6883 (2013.01); G01N 33/6893 (2013.01); C12Q 2600/156 (2013.01)

Citation (search report)

See references of WO 9845322A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9845322 A2 19981015; WO 9845322 A3 19990415; AU 7071598 A 19981030; CA 2287084 A1 19981015; EP 0971952 A2 20000119; JP 2001522241 A 20011113

INPADOC legal status

2004-06-23 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20031101

2000-01-19 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991019

2000-01-19 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-01-19 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free Format Text: AL PAYMENT 19991019;LT PAYMENT 19991019;LV PAYMENT 19991019;MK PAYMENT 19991019;RO PAYMENT 19991019;SI PAYMENT 19991019