Global Patent Index - EP 0972021 A1

EP 0972021 A1 2000-01-19 - EXTRACELLULAR/EPIDERMAL GROWTH FACTOR LIKE PROTEIN

Title (en)

EXTRACELLULAR/EPIDERMAL GROWTH FACTOR LIKE PROTEIN

Title (de)

DEM EXTRAZELLULÄREN EPIDERMALEN WACHSTUMSFAKTOR ÄHNLICHES PROTEIN.

Title (fr)

PROTEINE SEMBLABLE AU FACTEUR DE CROISSANCE EXTRACELLULAIRE/EPIDERMIQUE

Publication

EP 0972021 A1 (EN)

Application

EP 97921151 A

Priority

US 9706020 W

Abstract (en)

[origin: WO9846746A1] The present invention discloses extracellular/epidermal growth factor polypeptides and polynucleotides encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques and therapeutic uses of the polypeptides which include induction of DNA synthesis, stimulating wound healing, treating neurological disorders, treating ocular disorders, treating kidney and liver disorders and stimulating embryogenesis and angiogenesis. Also disclosed are antagonists against such polypeptide and their use as a therapeutic to treat neoplasia. Also disclosed are diagnostic assays for detecting altered levels of the polypeptide of the present invention and mutations in the nucleic acid sequences which encode the polypeptides of the present invention.

IPC 1-7 (main, further and additional classification)

C12N 15/12; A61K 31/70; A61K 38/18; A61K 48/00; C07K 14/485; C07K 16/22; C12N 1/21; C12N 5/10; C12Q 1/68; G01N 33/50; G01N 33/53

IPC 8 full level (invention and additional information)

G01N 33/53 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 1/16 (2006.01); A61P 13/12 (2006.01); A61P 17/02 (2006.01); A61P 25/00 (2006.01); A61P 27/02 (2006.01); A61P 43/00 (2006.01); C07K 14/485 (2006.01); C07K 16/22 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12Q 1/68 (2006.01); G01N 33/68 (2006.01)

CPC (invention and additional information)

C07K 14/485 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01)

Citation (search report)

See references of WO 9846746A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9846746 A1 19981022; AU 2727197 A 19981111; AU 752206 B2 20020912; CA 2286351 A1 19981022; EP 0972021 A1 20000119; JP 2002511743 A 20020416

INPADOC legal status


2007-01-03 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20060622

2002-12-18 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20021104

2000-01-19 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991111

2000-01-19 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE