EP 0972021 A1 20000119 - EXTRACELLULAR/EPIDERMAL GROWTH FACTOR LIKE PROTEIN
Title (en)
EXTRACELLULAR/EPIDERMAL GROWTH FACTOR LIKE PROTEIN
Title (de)
DEM EXTRAZELLULÄREN EPIDERMALEN WACHSTUMSFAKTOR ÄHNLICHES PROTEIN.
Title (fr)
PROTEINE SEMBLABLE AU FACTEUR DE CROISSANCE EXTRACELLULAIRE/EPIDERMIQUE
Publication
Application
Priority
US 9706020 W 19970411
Abstract (en)
[origin: WO9846746A1] The present invention discloses extracellular/epidermal growth factor polypeptides and polynucleotides encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques and therapeutic uses of the polypeptides which include induction of DNA synthesis, stimulating wound healing, treating neurological disorders, treating ocular disorders, treating kidney and liver disorders and stimulating embryogenesis and angiogenesis. Also disclosed are antagonists against such polypeptide and their use as a therapeutic to treat neoplasia. Also disclosed are diagnostic assays for detecting altered levels of the polypeptide of the present invention and mutations in the nucleic acid sequences which encode the polypeptides of the present invention.
IPC 1-7
C12N 15/12; C07K 14/485; C07K 16/22; G01N 33/50; G01N 33/53; A61K 31/70; A61K 38/18; A61K 48/00; C12Q 1/68; C12N 1/21; C12N 5/10
IPC 8 full level
A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 1/16 (2006.01); A61P 13/12 (2006.01); A61P 17/02 (2006.01); A61P 25/00 (2006.01); A61P 27/02 (2006.01); A61P 43/00 (2006.01); C07K 14/485 (2006.01); C07K 16/22 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
A61P 1/16 (2017.12); A61P 13/12 (2017.12); A61P 17/02 (2017.12); A61P 25/00 (2017.12); A61P 27/02 (2017.12); A61P 43/00 (2017.12); C07K 14/485 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01)
Citation (search report)
See references of WO 9846746A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9846746 A1 19981022; AU 2727197 A 19981111; AU 752206 B2 20020912; CA 2286351 A1 19981022; EP 0972021 A1 20000119; JP 2002511743 A 20020416
DOCDB simple family (application)
US 9706020 W 19970411; AU 2727197 A 19970411; CA 2286351 A 19970411; EP 97921151 A 19970411; JP 54383498 A 19970411