EP 0972200 A1 20000119 - SCREENING AND TREATMENT USING COMPLEMENT REGULATOR OR RECEPTOR PROTEINS
Title (en)
SCREENING AND TREATMENT USING COMPLEMENT REGULATOR OR RECEPTOR PROTEINS
Title (de)
SCREENING UND BEHANDLUNG MIT REGULATOREN UND REZEPTOREN DES KOMPLEMENTSYSTEMS
Title (fr)
CRIBLAGE ET TRAITEMENT AU MOYEN D'UN REGULATEUR DU COMPLEMENT OU DE PROTEINES RECEPTRICES DU COMPLEMENT
Publication
Application
Priority
- US 9804492 W 19980306
- US 81248197 A 19970306
- US 3861597 P 19970306
Abstract (en)
[origin: WO9839659A1] Methods of screening for cancers or treating cancers or autoimmune disorders are disclosed. In an aspect of the present invention, the screening methods are based on the detection of complement C3 or C3 related protein, or a nucleic acid molecule encoding the same, found to be associated with the presence of cancer. Additional screening methods are based on the use of complement regulators Factor I or DAF, or complement receptors 1 or 3. Preferred embodiments to the methods include detection based on immunological properties, physical properties, enzymatic properties and combinations thereof, or detection of a nucleic acid molecule encoding antigen based on nucleic acid amplification.
IPC 1-7
IPC 8 full level
A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); C07K 14/472 (2013.01); G01N 33/57496 (2013.01); C12Q 1/6886 (2013.01)
Citation (search report)
See references of WO 9839659A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9839659 A1 19980911; AU 6451998 A 19980922; EP 0972200 A1 20000119; JP 2001515589 A 20010918
DOCDB simple family (application)
US 9804492 W 19980306; AU 6451998 A 19980306; EP 98910227 A 19980306; JP 53888298 A 19980306