Global Patent Index - EP 0973522 A1

EP 0973522 A1 2000-01-26 - TOPICAL GEL COMPOSITION CONTAINING A COMBINATION OF A NSAID AND A XANTHINE DERIVATIVE

Title (en)

TOPICAL GEL COMPOSITION CONTAINING A COMBINATION OF A NSAID AND A XANTHINE DERIVATIVE

Title (de)

TOPISCHE GEL ZUSAMMENSTELLUNG DIE EINE KOMBINATION AUS EINEM NSAID UND EINEM XANTHINDERIVAT ENTHALTEN

Title (fr)

COMPOSITION DE GEL TOPIQUE CONTENANT UNE COMBINAISON D'UN MAINS ET D'UN DERIVE DE XANTHINE

Publication

EP 0973522 A1 (EN)

Application

EP 97933190 A

Priority

  • GB 9613457 A
  • US 9711205 W

Abstract (en)

[origin: WO9749405A1] Topical gel composition comprising: (a) from about 0.1 % to about 10 % by weight of a non-steroidal anti-inflammatory drug selected from a propionic acid derivative, acetic acid derivative, fenamic acid derivative, biphenylcarboxylic acid derivative and an oxicam, and salts thereof, and mixtures thereof; (b) from about 0.1 % to about 10 % by weight of xanthine derivative having general formula (I), wherein R1, R2 and R3 are each independently selected from a hydrogen atom, a methyl or ethyl group, and at least two of R1, R2 and R3 are methyl or ethyl groups, or mixtures thereof: (c) from about 0.5 % to about 10 % by weight of gelling agent; (d) from about 5 % to about 60 % by weight of cosolvent for said non-steroidal anti-inflammatory drug and said xanthine derivative; (e) from about 10 % to about 90 % by weight of water. The compositions of the invention provide enhanced product stability and clarity and analgesic and anti-inflammatory activity.

IPC 1-7 (main, further and additional classification)

A61K 31/52; A61K 31/54

IPC 8 full level (invention and additional information)

A61K 9/00 (2006.01); A61K 31/00 (2006.01); A61K 31/19 (2006.01); A61K 31/192 (2006.01); A61K 31/195 (2006.01); A61K 31/196 (2006.01); A61K 31/40 (2006.01); A61K 31/403 (2006.01); A61K 31/404 (2006.01); A61K 31/52 (2006.01); A61K 31/535 (2006.01); A61K 31/536 (2006.01); A61K 31/54 (2006.01); A61K 31/60 (2006.01); A61K 31/603 (2006.01); A61K 47/10 (2006.01); A61K 47/32 (2006.01); A61P 25/00 (2006.01); A61P 25/02 (2006.01); A61P 29/00 (2006.01); A61P 43/00 (2006.01)

CPC (invention and additional information)

A61K 9/0014 (2013.01); A61K 31/52 (2013.01); A61K 31/54 (2013.01); A61K 47/10 (2013.01); A61K 47/32 (2013.01)

Combination set (CPC)

  1. A61K 31/54 + A61K 31/52
  2. A61K 31/52 + A61K 31/195
  3. A61K 31/52 + A61K 31/19
  4. A61K 31/52 + A61K 2300/00
  5. A61K 31/54 + A61K 2300/00

Citation (search report)

See references of WO 9749405A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9749405 A1 19971231; AU 3643897 A 19980114; BR 9709997 A 19990810; CA 2258199 A1 19971231; CZ 9804091 A3 19990414; EP 0973522 A1 20000126; GB 9613457 D0 19960828; HU 9903835 A2 20001028; HU 9903835 A3 20010328; IL 127426 D0 19991028; JP H11513037 A 19991109; KR 20000022245 A 20000425; NO 986042 A 19990226; NO 986042 D0 19981222; NZ 333180 A 20000929; TR 9802701 T2 19990322

INPADOC legal status


2007-02-02 [REG HK WD] APPLICATIONS WITHDRAWN, DEEMED TO BE WITHDRAWN, OR REFUSED AFTER PUBLICATION IN HONG KONG

- Document: HK 1025253

2002-03-27 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20010920

2001-06-27 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010509

2000-01-26 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19981221

2000-01-26 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE