EP 0973549 A2 20000126 - INTRAVENOUS IMMUNE GLOBULIN FORMULATION CONTAINING A NON-IONIC SURFACE ACTIVE AGENT WITH IMPROVED PHARMACOKINETIC PROPERTIES
Title (en)
INTRAVENOUS IMMUNE GLOBULIN FORMULATION CONTAINING A NON-IONIC SURFACE ACTIVE AGENT WITH IMPROVED PHARMACOKINETIC PROPERTIES
Title (de)
INTRAVENÖSE IMMUNGLOBULINZUSAMMENSETZUNGEN DIE EIN NICHTIONISCHES OBERFLÄCHE-AKTIVES AGENS ENTHÄLT MIT VERBESSERTEN PHARMAKOKINETISCHEN EIGENSCHAFTEN
Title (fr)
COMPOSITION INTRAVEINEUSE D'IMMUNOGLOBULINE CONTENANT UN TENSIOACTIF NON IONIQUE AUX PROPRIETES PHARMACOCINETIQUES AMELIOREES
Publication
Application
Priority
- CA 9800325 W 19980407
- US 4192197 P 19970407
Abstract (en)
[origin: WO9844948A2] Addition of a non-ionic surface active agent to an immune globulin formulation extends the serum half-life of relatively pure and non-aggregated immune globulin suitable for intravenous injectionor infusion. The non-ionic surface active agent may be a sorbitan ester or a polyoxyethylene sorbitan ester of a fatty acid. Formulations of the present invention is therapeutically advantageous over conventional formulations in that an extended serum half-life of the immune globulin improves its therapeutic effectiveness, reduces the frequency of drug administration and/or lowers the therapeutic effective dosage required and cost of treatment.
IPC 1-7
IPC 8 full level
A61K 39/395 (2006.01); C07K 16/34 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61K 39/39591 (2013.01); C07K 16/34 (2013.01); A61K 38/00 (2013.01); A61K 2121/00 (2013.01)
Citation (search report)
See references of WO 9844948A2
Citation (third parties)
Third party :
- WO 9503826 A1 19950209 - PASTEUR MERIEUX SERUMS VACC [FR], et al
- US 4093606 A 19780606 - COVAL MYER LOUIS
- US 5219999 A 19930615 - SUZUKI TOHRU [JP], et al
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9844948 A2 19981015; WO 9844948 A3 19990211; WO 9844948 B1 19990401; AU 6914998 A 19981030; EP 0973549 A2 20000126
DOCDB simple family (application)
CA 9800325 W 19980407; AU 6914998 A 19980407; EP 98914750 A 19980407