Global Patent Index - EP 0973549 A2

EP 0973549 A2 2000-01-26 - INTRAVENOUS IMMUNE GLOBULIN FORMULATION CONTAINING A NON-IONIC SURFACE ACTIVE AGENT WITH IMPROVED PHARMACOKINETIC PROPERTIES

Title (en)

INTRAVENOUS IMMUNE GLOBULIN FORMULATION CONTAINING A NON-IONIC SURFACE ACTIVE AGENT WITH IMPROVED PHARMACOKINETIC PROPERTIES

Title (de)

INTRAVENÖSE IMMUNGLOBULINZUSAMMENSETZUNGEN DIE EIN NICHTIONISCHES OBERFLÄCHE-AKTIVES AGENS ENTHÄLT MIT VERBESSERTEN PHARMAKOKINETISCHEN EIGENSCHAFTEN

Title (fr)

COMPOSITION INTRAVEINEUSE D'IMMUNOGLOBULINE CONTENANT UN TENSIOACTIF NON IONIQUE AUX PROPRIETES PHARMACOCINETIQUES AMELIOREES

Publication

EP 0973549 A2 (EN)

Application

EP 98914750 A

Priority

  • CA 9800325 W
  • US 4192197 P

Abstract (en)

[origin: WO9844948A2] Addition of a non-ionic surface active agent to an immune globulin formulation extends the serum half-life of relatively pure and non-aggregated immune globulin suitable for intravenous injectionor infusion. The non-ionic surface active agent may be a sorbitan ester or a polyoxyethylene sorbitan ester of a fatty acid. Formulations of the present invention is therapeutically advantageous over conventional formulations in that an extended serum half-life of the immune globulin improves its therapeutic effectiveness, reduces the frequency of drug administration and/or lowers the therapeutic effective dosage required and cost of treatment.

IPC 1-7 (main, further and additional classification)

A61K 39/395

IPC 8 full level (invention and additional information)

A61K 39/395 (2006.01); C07K 16/34 (2006.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

A61K 39/39591 (2013.01); C07K 16/34 (2013.01); A61K 38/00 (2013.01); A61K 2121/00 (2013.01)

Citation (third parties)

Third party :

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family

WO 9844948 A2 19981015; WO 9844948 A3 19990211; WO 9844948 B1 19990401; AU 6914998 A 19981030; EP 0973549 A2 20000126