Global Patent Index - EP 0973549 A2

EP 0973549 A2 2000-01-26 - INTRAVENOUS IMMUNE GLOBULIN FORMULATION CONTAINING A NON-IONIC SURFACE ACTIVE AGENT WITH IMPROVED PHARMACOKINETIC PROPERTIES

Title (en)

INTRAVENOUS IMMUNE GLOBULIN FORMULATION CONTAINING A NON-IONIC SURFACE ACTIVE AGENT WITH IMPROVED PHARMACOKINETIC PROPERTIES

Title (de)

INTRAVENÖSE IMMUNGLOBULINZUSAMMENSETZUNGEN DIE EIN NICHTIONISCHES OBERFLÄCHE-AKTIVES AGENS ENTHÄLT MIT VERBESSERTEN PHARMAKOKINETISCHEN EIGENSCHAFTEN

Title (fr)

COMPOSITION INTRAVEINEUSE D'IMMUNOGLOBULINE CONTENANT UN TENSIOACTIF NON IONIQUE AUX PROPRIETES PHARMACOCINETIQUES AMELIOREES

Publication

EP 0973549 A2 (EN)

Application

EP 98914750 A

Priority

  • CA 9800325 W
  • US 4192197 P

Abstract (en)

[origin: WO9844948A2] Addition of a non-ionic surface active agent to an immune globulin formulation extends the serum half-life of relatively pure and non-aggregated immune globulin suitable for intravenous injectionor infusion. The non-ionic surface active agent may be a sorbitan ester or a polyoxyethylene sorbitan ester of a fatty acid. Formulations of the present invention is therapeutically advantageous over conventional formulations in that an extended serum half-life of the immune globulin improves its therapeutic effectiveness, reduces the frequency of drug administration and/or lowers the therapeutic effective dosage required and cost of treatment.

IPC 1-7 (main, further and additional classification)

A61K 39/395

IPC 8 full level (invention and additional information)

A61K 39/395 (2006.01); C07K 16/34 (2006.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

A61K 39/39591 (2013.01); C07K 16/34 (2013.01); A61K 38/00 (2013.01); A61K 2121/00 (2013.01)

Citation (third parties)

Third party :

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9844948 A2 19981015; WO 9844948 A3 19990211; WO 9844948 B1 19990401; AU 6914998 A 19981030; EP 0973549 A2 20000126

INPADOC legal status


2008-01-30 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20070807

2007-04-25 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20050303

2005-04-20 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20050303

2000-01-26 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19991108

2000-01-26 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE